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Displaying results 111 - 120 of 10000 in total
  1. Drug

    Paliperidone

    go.drugbank.com/drugs/DB01267
    ApprovedInvestigational

    Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. … It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism.

    Products: INVEGA Sustenna Prolonged Release Suspension for IM Injection 25mg/0.25 ml, INVEGA Sustenna Prolonged Release Suspension for IM Injection 50mg/0.5 ml
  2. Drug

    Esmolol

    go.drugbank.com/drugs/DB00187
    ApprovedInvestigationalWithdrawn

    It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate of heart contractions. … Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker.

    Products: Brevibloc Liq IV 10mg/ml, Brevibloc Liq IV 250mg/ml
  3. Drug

    Tocilizumab

    go.drugbank.com/drugs/DB06273
    ApprovedInvestigational

    [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. … Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions.

    Products: ACTEMRA 200 MG/10 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 1 ADET, ACTEMRA 200 MG/10 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 4 ADET
  4. Drug

    Cefuroxime

    go.drugbank.com/drugs/DB01112
    ApprovedInvestigational

    It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.

    Synonyms: (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidMixtures: TUGENS 250 MG IM ENJEKSIYON ICIN TOZ ICEREN FLAKON, 1 ADET, TUGENS 750 MG IM ENJEKSIYON ICIN TOZ ICEREN FLAKON, 1 ADET
  5. Drug

    Sulbactam

    go.drugbank.com/drugs/DB09324
    ApprovedInvestigational

    [L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.[A263296] … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus.

    Mixtures: SULPERAZON 1G IM/IV, UNASYN IM/IV 1.5GProducts: B-LAKTAM 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 5 ADET, B-LAKTAM 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 100 ADET
  6. Drug

    Beroctocog alfa

    go.drugbank.com/drugs/DB14473
    ApprovedInvestigational

    Mixtures: ALPHANATE FOR INJECTION 250 iu/vial, ALPHANATE FOR INJECTION 1000 iu/vialProducts: KOATE-DVI 250 IU/5 ML IV ENJEKSİYON İÇİN LİYOFİLZE TOZ İÇEREN FLAKON, KOATE-DVI 500 IU/5 ML IV ENJEKSİYON İÇİN LİYOFİLZE TOZ İÇEREN FLAKON
  7. Drug

    Furosemide

    go.drugbank.com/drugs/DB00695
    ApprovedInvestigationalVet approved

    Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. … in emergency clinical situations.

    Products: Lasix Injection 10mg/ml - Im IV, FUROSON 40 MG/4 ML IM/IV AMPUL, 5 ADET
  8. Drug

    Protein C

    go.drugbank.com/drugs/DB11312
    ApprovedInvestigational

    Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. … Protein C is available in concentrated form as the product Ceprotin, which is indicated for use in pediatric and adult patients with severe congenital protein C deficiency for the prevention and treatment

    Mixtures: COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET, COFACT 500 IU/20 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADETProducts: CEPROTIN 500 IU IV ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON
  9. Drug

    D-glucose

    go.drugbank.com/drugs/DB01914
    ApprovedInvestigationalVet approved

    [A19399] It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. … It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis).

    Synonyms: D-Glucose in linear formMixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose
  10. Drug

    Levocarnitine

    go.drugbank.com/drugs/DB00583
    ApprovedInvestigational

    It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

    Synonyms: L-Carnitine, (-)-L-CarnitineMixtures: Q 10 Suprabio +L-Carnitine