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Displaying results 111 - 120 of 10000 in total
  1. Drug

    5-O-phosphono-alpha-D-ribofuranosyl diphosphate

    go.drugbank.com/drugs/DB01632
    ApprovedWithdrawn

    The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.

    Synonyms: 5-Phosphoribosyl 1-pyrophosphate, 5-Phospho-alpha-D-ribose 1-diphosphate
  2. Drug

    Aminolevulinic acid

    go.drugbank.com/drugs/DB00855
    ApprovedInvestigational

    A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]

    Categories: Amino Acids, Peptides, and Proteins, Skin and Mucous Membrane AgentsSynonyms: 5-ALA, 5-Aminolevulinic acid
  3. Drug

    Secobarbital

    go.drugbank.com/drugs/DB00418
    ApprovedVet approved

    Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties.

    Categories: Heterocyclic Compounds, 1-Ring, Hypnotics and SedativesSynonyms: 5-(1-methylbutyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-allyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
  4. Drug

    Leflunomide

    go.drugbank.com/drugs/DB01097
    ApprovedInvestigational

    Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. … Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.

    Categories: Heterocyclic Compounds, 1-Ring, Leflunomide and metaboliteSynonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide
  5. Drug

    Strychnine

    go.drugbank.com/drugs/DB15954
    Experimental

    Synonyms: Strychnidin-10-oneCategories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household setting
  6. Drug

    Methohexital

    go.drugbank.com/drugs/DB00474
    Approved

    An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.

    Categories: Heterocyclic Compounds, 1-Ring, Hypnotics and SedativesSynonyms: 5-allyl-1-methyl-5-(1-methyl-2-pentynyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid
  7. Drug

    Mesalazine

    go.drugbank.com/drugs/DB00244
    ApprovedInvestigational

    Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent … Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation

    Synonyms: m-Aminosalicylic acid, 5-ASAProducts: KOLESA 250 MG SUPOZİTUVAR, 10 ADET, SALOFALK 250 MG SUPOZITUAR, 10 ADET
  8. Drug

    Streptococcus pneumoniae type 5 capsular polysaccharide antigen

    go.drugbank.com/drugs/DB10323
    ApprovedInvestigational

    Streptococcus pneumoniae type 5 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 5 of *Streptococcus pneumoniae*. … It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.

    Mixtures: PNEUMOVAX 23 0,5 ML ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET, SII PNEUMOSIL Pneumococcal Polysaccharide Conjugate Vaccine (Adsorbed) (10-Valent) SUSPENSION FOR INJECTION (MULTIDOSE - 5 DOSE)Synonyms: pneumococcal capsular polysaccharide type 5 vaccine, Streptococcus pneumoniae type 5 capsular polysaccharide antigen
  9. Drug

    Nitrofurantoin

    go.drugbank.com/drugs/DB00698
    ApprovedInvestigationalVet approved

    [A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole].[A179830] Nitrofurantoin was granted FDA approval on 6 February 1953.[L6895] … [L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein.

    Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesSynonyms: N-(5-Nitrofurfurylidene)-1-aminohydantoin, 1-((5-nitrofurfurylidene)amino)hydantoin
  10. Drug

    Homidium

    go.drugbank.com/drugs/DB17031
    Investigational

    Homidium is a group II compound with trypanocidal effects.[A253017]

    Categories: Indicators and Reagents, Heterocyclic Compounds, 3-RingSynonyms: 2,7-diamino-10-ethyl-9-phenylphenanthridinium, 2,7-diamino-9-phenyl-10-ethylphenanthridinium