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Displaying results 1191 - 1200 of 3483 in total
  1. Drug

    (1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid

    go.drugbank.com/drugs/DB03455
    Experimental

    (1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid is a solid. This compound belongs to the indole-3-acetic acid derivatives. … These are compounds containing an acetic acid (or a derivative) linked to the C3 carbon atom of an indole. (1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid is known to target interleukin-2.

    Synonyms: (1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid
  2. Drug

    Tioconazole

    go.drugbank.com/drugs/DB01007
    Approved

    Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane.

    Mixtures: GYNOMAX XL 200 MG/ 300 MG/100 MG VAJINAL OVÜL, 3 ADET, GYNOMAX L VAJINAL OVUL, 7 ADETCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C19 Inhibitors
  3. Drug

    Elacestrant

    go.drugbank.com/drugs/DB06374
    ApprovedInvestigational

    [A256828,A256863,L44948] Other types of endocrine therapy, such as selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs), may lead to drug resistance over time; therefore, the use

    Synonyms: (2R)-2-(2-(ethyl-((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxy-phenyl)tetralin-6-ol, (6R)-6-(2-(ethyl((4-(2- (ethylamino)ethyl)phenyl)methyl)amino)-4-methoxyphenyl)- 5,6,7,8-tetrahydronaphthalen-2-olCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  4. Drug

    Pseudoephedrine

    go.drugbank.com/drugs/DB00852
    Approved

    Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system. Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first ...

    Synonyms: L(+)-psi-Ephedrine, L-(+)-PseudoephedrineMixtures: P-Tuss DM, Viravan P
  5. Drug

    Deleobuvir

    go.drugbank.com/drugs/DB14850
    Investigational

    Deleobuvir is under investigation in clinical trial NCT01983566 (Effect of Food and Increased Gastric pH Value on Bioavailability of a Single Dose of BI 207127 in Healthy Caucasian and Japanese Subjects

  6. Drug

    MLN8054

    go.drugbank.com/drugs/DB13061
    Investigational

    MLN8054 has been used in trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies.

  7. Drug

    Tetrathiomolybdate

    go.drugbank.com/drugs/DB05088
    Investigational

    Tetrathiomolybdate is an oral, small-molecule, anticopper agent that is highly specific for lowering the levels of free copper in serum. COPREXA has completed pivotal clinical trials for the treatment of neurologic Wilson's disease. It i...

  8. Drug

    CRx-139

    go.drugbank.com/drugs/DB05744
    Experimental

    CRx-139 is an oral synergistic combination drug candidates with novel mechanisms of action targeting multiple biological pathways simultaneously. It is a dissociated steroid designed to enhance the immuno-modulatory activity of a low-dos...

  9. Drug

    Amediplase

    go.drugbank.com/drugs/DB06679
    Experimental

    Amediplase is a recombinant chimeric plasminogen activator, consisting of the kringle 2 domain from the A-chain of tissue plasminogen activator (t-PA) and the carboxy terminal region of pro-urokinase.

  10. Drug

    Aminacrine

    go.drugbank.com/drugs/DB11561
    Investigational

    It is also used as an intracellular pH indicator.