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Pyrazinamide
go.drugbank.com/drugs/DB00339ApprovedInvestigationalA pyrazine that is used therapeutically as an antitubercular agent.
Synonyms: 2-carbamylpyrazine, 2-pyrazinecarboxamideMixtures: RINCURE ® 3 FDC TABLETAS CON PELICULA, PRO TB 4Trypsin
go.drugbank.com/drugs/DB11237ApprovedInvestigationalVet approvedTrypsin contains a nucleophilic residue Ser in the enzyme active site which attacks the carbonyl moiety of the substrate peptide bond to form an acyl-enzyme intermediate [A27241]. … Trypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals.
Rosiglitazone
go.drugbank.com/drugs/DB00412ApprovedInvestigationalRecent research has suggested that rosiglitazone may also be of benefit to a subset of patients with Alzheimer's disease not expressing the ApoE4 allele. … Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs.
Synonyms: (±)-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione, (RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedionInternational brands: Sheng MinFomivirsen
go.drugbank.com/drugs/DB06759ApprovedWithdrawnFomivirsen is a antisense 21 mer phosphorothioate oligonucleotide. … As a complementary nucleotide to the messenger RNA of the major immediate-early region proteins of human cytomegalovirus, it disrupts the replication of the virus through an antisense mechanism [L1428]
Categories: Compounds used in a research, industrial, or household settingOzanimod
go.drugbank.com/drugs/DB12612ApprovedInvestigational[A176474] Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. … Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease.
Mixtures: ZEPOSIA 7-Day Starter Pack, ZEPOSIA 7-Day Starter PackCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesSulconazole
go.drugbank.com/drugs/DB06820ApprovedSulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an effective treatment for tinea cruris and tinea corporis … Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP1A2 InhibitorsRose bengal
go.drugbank.com/drugs/DB11182ApprovedInvestigationalRose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. … A direct cytotoxic effect of Rose bengal on microorganisms and cancer cells has been observed, questioning its potential antitumor actions via intralesional injections.
Categories: Heterocyclic Compounds, 3-Ring, Compounds used in a research, industrial, or household settingPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigationalPioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus. … failure, bladder cancer) and the availability of safer and more effective alternatives for patients with type 2 diabetes mellitus.
Synonyms: (±)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dioneMixtures: INCRESINA P, PIONIX M 850Human Rho(D) immune globulin
go.drugbank.com/drugs/DB11597ApprovedRho (D) immune globulin is available as a sterile, lyophilized or liquid gamma globulin (IgG) fraction containing antibodies to the Rh0 (D) antigen (D antigen) under the name Rhophylac (IM/IV). … Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn).
Categories: Human Immunoglobulin G, anti-D (rh) immunoglobulinSynonyms: IGG, Rho (D), Anti-D immunoglobulinMoxidectin
go.drugbank.com/drugs/DB11431ApprovedInvestigationalVet approvedIt was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of the milbemycin class. … Moxidectin differs by the absence of a disaccharide moiety on carbon 13, a substituted olefinic side chain at carbon 25 and a unique methoxime moiety at carbon 23.
Categories: Compounds used in a research, industrial, or household setting