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Axitinib
go.drugbank.com/drugs/DB06626ApprovedInvestigationalIt is reported to exhibit potency that is 50-450 times higher than that of the first generation VEGFR inhibitors.[L6676] Axitinib is an indazole derivative. … [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations.
Synonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamideProducts: INLYTA (TABLETS 1 MG), INLYTA (TABLETS 5 MG)Strontium ranelate
go.drugbank.com/drugs/DB09267ApprovedWithdrawnAvailable for prescription use for a time in some parts of the world as Protelos (strontium ranelate) 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an … This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and, simultaneously, reduces the resorption of bone by osteoclasts.
Mixtures: FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 30 ADET, FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 60 ADETProducts: RASBY 2 G ORAL SUSPANSIYON ICIN GRANUL ,84 PAKET, DIOSS 2 G EFERVESAN TABLET, 56 ADETChlorambucil
go.drugbank.com/drugs/DB00291ApprovedInvestigationalAlthough it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Synonyms: N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid, N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acidProducts: Leukeran 2 mg - Filmtabletten, LEUKERAN 2 MG TABLET, 25 ADETIoversol
go.drugbank.com/drugs/DB09134ApprovedInvestigational[L41780] Ioversol was approved by the FDA in 1989 and is currently indicated for computed tomographic (CT) imaging and contrast enhancement in peripheral arteriography, coronary arteriography, and left … Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamideDabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigational[A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated. … [A177463] In contrast to warfarin, because its anticoagulant effects are predictable, lab monitoring is not necessary.[A177463] Dabigatran etexilate was approved by the FDA in 2010.[L6022]
Products: PRADAXA 75 MG SERT KAPSUL, 10 ADET, PRADAXA 75 MG SERT KAPSUL, 60 ADETTioconazole
go.drugbank.com/drugs/DB01007ApprovedIn addition to being an antifungal, tioconazole also has antibacterial effects on certain Gram-positive cocci bacteria.[L50166] … In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability.
Mixtures: TIOZONE KREM, 30 G, TRİVAG 300 MG / 200 MG/ 100 MG OVÜL, 3 ADETProducts: TIOCONAZOLO EG, TIODERMA %1 DERMAL 20 ML LOSYONOxybuprocaine
go.drugbank.com/drugs/DB00892ApprovedInvestigationalOxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology.
Synonyms: 4-Amino-3-n-butoxy-benzoesäure-diäthylaminoäthylesterProducts: BENOXINATE % 0.4 GÖZ DAMLASI, 10 ML, Novain 4 mg/ml Augentropfen, LösungAcarbose
go.drugbank.com/drugs/DB00284ApprovedInvestigationalAcarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines. … Acarbose is therefore used in conjunction with diet, exercise, and other pharmacotherapies for the management of blood sugar levels in patients with type 2 diabetes.
Categories: Drugs Used in DiabetesProducts: ACARBOSA 50 MG, ACNOR 50 MG TABLET, 30 ADETPrucalopride
go.drugbank.com/drugs/DB06480ApprovedInvestigational[A40254] Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009,[A40250] in Canada on December 7, 2011 and by the FDA on December 17, 2018.[L4880]
Products: Resolor Film-coated Tablet 2 mg, Resolor Film-coated Tablet 1 mgUpadacitinib
go.drugbank.com/drugs/DB15091ApprovedInvestigational[L10896] In December 2019, it was additionally approved by the European Commission and Health Canada.[L10899,L42540] Upadacitinib is marketed under the brand name RINVOQ for oral administration. … [A189165] Despite a variety of therapeutic agents available for treatment, up to 40% of the patients do not respond to current therapies, including biological therapies.
Products: Rinvoq 30 mg Uzatılmış Salımlı Tablet, 28 ADET, RINVOQ 30 mg extended-release film coated tablets