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Peroxisome proliferator-activated receptor gamma coactivator 1-beta
go.drugbank.com/bio_entities/BE0009812TargetHumansActivates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids.
Polypeptides: Peroxisome proliferator-activated receptor gamma coactivator 1-betaSynonyms: PGC-1-related estrogen receptor alpha coactivatorLeukocyte immunoglobulin-like receptor subfamily B member 2
go.drugbank.com/bio_entities/BE0010561TargetHumansReceptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:11169396, PubMed:12853576, PubMed:16455647, PubMed:20448110, PubMed:27859042).
Polypeptides: Leukocyte immunoglobulin-like receptor subfamily B member 2Synonyms: Leukocyte immunoglobulin-like receptor 2, Monocyte/macrophage immunoglobulin-like receptor 10Leukocyte immunoglobulin-like receptor subfamily B member 1
go.drugbank.com/bio_entities/BE0010562TargetHumansReceptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:16455647, PubMed:28636952). … Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response.
Polypeptides: Leukocyte immunoglobulin-like receptor subfamily B member 1Synonyms: Leukocyte immunoglobulin-like receptor 1, Monocyte/macrophage immunoglobulin-like receptor 7Leukocyte immunoglobulin-like receptor subfamily B member 4
go.drugbank.com/bio_entities/BE0017129TargetHumansReceptor for apolipoprotein APOE (PubMed:30333625). Receptor for ALCAM/CD166 (PubMed:29263213). … Inhibitory receptor involved in the down-regulation of the immune response and the development of immune tolerance (PubMed:11875462). Receptor for FN1 (PubMed:34089617).
Polypeptides: Leukocyte immunoglobulin-like receptor subfamily B member 4Synonyms: Monocyte inhibitory receptor HM18, Leukocyte immunoglobulin-like receptor 5Mas-related G protein-coupled receptor member X2
go.drugbank.com/bio_entities/BE0018408TargetHumansMast cell-specific G protein-coupled receptor for basic secretagogues, which regulates mast cell degranulation and itch-related hypersensitivity reactions (PubMed:22069323, PubMed:25517090, PubMed:28288109 … Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37
Polypeptides: Mas-related G protein-coupled receptor member X2Function: C-C chemokine receptor activityFondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalknee surgery); to prevent VTE in patients undergoing abdominal surgery who are are at high risk of thromboembolic complications; in the treatment of deep vein thrombosis (DVT) and pumonary embolism (PE
Triple-Negative Breast Cancer
go.drugbank.com/conditions/DBCOND0068542Drugs: AtezolizumabSynonyms: Breast Carcinoma That is Estrogen Receptor, Progesterone Receptor, and Her2 NegativeImetelstat
go.drugbank.com/drugs/DB14909ApprovedInvestigationalImetelstat is a first-in-class 18-amino acid oligonucleotide that directly and competitively inhibits human telomerase. It is used to treat anemia in patients with myelodysplastic syndromes (MDS), a group of hematologic disorders charact...
Coagulation factor VII human
go.drugbank.com/drugs/DB13150ApprovedInvestigationalCoagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
Mixtures: UMAN COMPLEX, UMAN COMPLEXDehydrocholic acid
go.drugbank.com/drugs/DB11622ApprovedThe use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.