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Displaying results 1241 - 1250 of 10000 in total
  1. Drug

    Antihemophilic factor (recombinant), PEGylated

    go.drugbank.com/drugs/DB09329
    ApprovedInvestigational

    with at least one molecule of polyethylene glycol (MW 20 kDa) [FDA label]. … Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated

    Products: ADYNOVATE 500®IU / VIAL, ADYNOVATE 500 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION
  2. Drug

    Bosentan

    go.drugbank.com/drugs/DB00559
    ApprovedInvestigational

    Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise pr...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InducersSynonyms: 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide, p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
  3. Drug

    DL-alpha tocopheryl acetate

    go.drugbank.com/drugs/DB14477
    Approved

    Mixtures: Folika-MG, Tl-hem 150Products: BIOCAR-E 400 MG CAPSULA LIQUIDA, Aquasol E Drops 50unit/ml
  4. Drug

    Flutemetamol (18F)

    go.drugbank.com/drugs/DB09151
    ApprovedInvestigational

    It is used to evaluate Alzheimer's disease (AD) or other causes of cognitive decline as an Aβ-specific positron emission tomography (PET) ligand.[L35029]

    Products: VİZAMYL 150 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ML
  5. Drug

    Nicorandil

    go.drugbank.com/drugs/DB09220
    ApprovedInvestigationalWithdrawn

    Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivat...

    Products: Dancor 10 mg - Tabletten, Nicolan 10 mg - Tabletten
  6. Drug

    Perampanel

    go.drugbank.com/drugs/DB08883
    ApprovedInvestigational

    It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one
  7. Drug

    Tetracosactide

    go.drugbank.com/drugs/DB01284
    ApprovedInvestigational

    Tetracosactide exhibits the same activity as natural ACTH with regard to all its biological activities. … Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone.

    Products: Synacthen 0,25 mg/1 ml Ampulle, SYNACTHEN DEPOT 1 MG AMPUL, 1 ADET
  8. Drug

    Amithiozone

    go.drugbank.com/drugs/DB12829
    Investigational

    Amithiozone has been used in trials studying the treatment of Mycobacterium Avium-intracellulare Infection.

    Products: CITAZON 150 MG TABLET, 50 ADET, CİTAZON 150 MG TABLET, 500 ADET
  9. Drug

    Mavacamten

    go.drugbank.com/drugs/DB14921
    ApprovedInvestigational

    [A248440] Mavacamten was also approved by Health Canada in October 2022 and by EMA in July 2023 for the same indication.[L44106,L47471]

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesProducts: Camzyos 10 mg Sert Kapsül (14 adet), Camzyos 10 mg Sert Kapsül (28 adet)
  10. Drug

    Ajmaline

    go.drugbank.com/drugs/DB01426
    ApprovedWithdrawn

    It has also been used for many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and syncope. … In these cases, abnormal prolongation of the HV interval has been taken as a proof for infrahisian conduction defects tributary for permanent pacemaker implantation.

    Synonyms: (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo[3,2-b]quinolizine-8,13-diolProducts: Gilurytmal 5 mg/ml Injektionslösung und Konzentrat zur Herstellung einer Infusionslösung