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NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
go.drugbank.com/bio_entities/BE0000485TargetHumansCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor
Synonyms: Complex I-51kDDiacylglycerol acyltransferase/mycolyltransferase Ag85C
go.drugbank.com/bio_entities/BE0001688TargetMycobacterium tuberculosisThe antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They...
Synonyms: Antigen 85 complex CExenatide
go.drugbank.com/drugs/DB01276ApprovedInvestigational[L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension, was discontinued in 2021. … Bydureon BCise, an auto-injector extended-release formulation, remains available.[L42700]
Categories: Drugs Used in DiabetesProducts: BYDUREON® PEN, BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MGAlmitrine
go.drugbank.com/drugs/DB01430ApprovedAlmitrine is a respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. … It is used in the treatment of chronic obstructive pulmonary disease.
Categories: Compounds used in a research, industrial, or household settingMagnesium ascorbate
go.drugbank.com/drugs/DB14484ApprovedNutraceuticalMixtures: EnlCategories: Compounds used in a research, industrial, or household settingNADH dehydrogenase [ubiquinone] 1 subunit C2
go.drugbank.com/bio_entities/BE0000173TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-B14.5bIcodextrin
go.drugbank.com/drugs/DB00702ApprovedInvestigationalIcodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. … It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease.
Categories: Compounds used in a research, industrial, or household settingNonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnIt is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market. … N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants.
Categories: Compounds used in a research, industrial, or household settingCantharidin
go.drugbank.com/drugs/DB12328ApprovedInvestigationalinflammatory model or in cancer treatment. … Cantharidin is a naturally occurring odorless, colorless fatty substance of the terpenoid class that is produced as an oral fluid in the alimentary canal of the male blister beetle.
Categories: Compounds used in a research, industrial, or household settingSuccinate dehydrogenase
go.drugbank.com/bio_entities/BE0010253EnzymeTargetHumansIron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed … Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to
Synonyms: Flavoprotein subunit of complex II, Iron-sulfur subunit of complex II