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Macitentan
go.drugbank.com/drugs/DB08932ApprovedInvestigationalMacitentan differs from its predecessor [bosentan] in part due to its lower risk of hepatotoxicity. … Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013.
Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASProducts: MACITENT® 10 MG, MACITENTAN 10 MGTetracaine
go.drugbank.com/drugs/DB09085ApprovedInvestigationalVet approvedTetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Mixtures: Pliaglis 70 mg/g + 70 mg/g Creme, Pliaglis 70 mg/g + 70 mg/g creamCategories: Esters of Aminobenzoic Acid, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedA specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Mixtures: DEXGARD 30/30 MG MR KAPSUL, 60 ADET, LACOMBI 15/10 MG KAPSUL, 28 ADETProducts: Nu-domperidone 10 Mg Tablets, DOMPERIDONE FGPiperonyl butoxide
go.drugbank.com/drugs/DB09350ApprovedVet approvedIt has no pesticidal activity of its own, but acts to increase the activity of pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone. … Piperonyl butoxide is a semisynthetic derivative of safrole.
Mixtures: Dg Health Lice Killing Maximum StrengthCategories: Compounds used in a research, industrial, or household settingLevamlodipine
go.drugbank.com/drugs/DB09237ApprovedInvestigational[A188940] Levamlodipine was granted FDA approval on 19 December 2019.[L10833] … Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of [amlodipine], an antihypertensive medication.
Mixtures: VOLTRAMOS 2.5 MG/160 MG FILM KAPLI TABLET, 28 ADET, VOLTRAMOS 5 MG/160 MG FILM KAPLI TABLET, 28 ADETProducts: ALENCAL®2.5 MGAprepitant
go.drugbank.com/drugs/DB00673ApprovedInvestigationalAprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting (CI NV). … associated with initial and repeat courses of highly emetogenic cancer chemotherapy.
Mixtures: EMEND® 80 MG/125 MG, EMEND® 80 MG/125 MGProducts: Atanto 125 mg/80 mg Hartkapseln, Aprepitant ratiopharm 80 mg/125 mg HartkapselnProbenecid
go.drugbank.com/drugs/DB01032ApprovedInvestigationalIt inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. … Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Categories: combinations of sulfonamides, Preparations With No Effect on Uric Acid MetabolismProducts: PROBENECID TABLET 500 mgBenzatropine
go.drugbank.com/drugs/DB00245ApprovedInvestigationalThe generation of structure-activity relationships proved that benztropine derivatives with the presence of a chlorine substituent in the para position in one of the phenyl rings produces an increased … [A37914] Benztropine was developed by USL Pharma and officially approved by the FDA on 1996.[L5500]
Categories: Ethers of Tropine or Tropine DerivativesProducts: APO-BENZTROPINE TABLET 2 mg, COGENTIN INJECTION 2 mg/2 mlArtemether
go.drugbank.com/drugs/DB06697ApprovedInvestigationalThis combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp.
Mixtures: Riamet 20 mg/120 mg - Tabletten, ARTEMETERO 20 MG + LUMEFANTRINA 120 MG TABLETAPretomanid
go.drugbank.com/drugs/DB05154ApprovedInvestigationalPersistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality and a cause for significant concern. … and shorter duration of treatment with fewer drugs.
Categories: Drugs for Treatment of Tuberculosis