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Indacaterol
go.drugbank.com/drugs/DB05039ApprovedInvestigationalIt was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as Onbrez and in America as Arcapta Neohaler.
Agalsidase beta
go.drugbank.com/drugs/DB00103ApprovedInvestigational[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009. … [A220343] Agalsidase beta was granted FDA approval on 24 April 2003.[L16383]
Ulipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationaldebated due to ethical concerns related to abortion (Rosato et al, 2016). … A recent systematic review proclaimed that the majority of available evidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily
Products: Ella Tablet 30mg, ELLA TABLET 30MGErdosteine
go.drugbank.com/drugs/DB05057ApprovedInvestigationaland more pronounced amelioration of clinical symptoms compared with placebo. … 300mg twice daily reduced cough (both frequency and severity) and sputum viscosity more quickly and more effectively than placebo and reduced the adhesivity of sputum more effectively than ambroxol 30mg
Cipaglucosidase alfa
go.drugbank.com/drugs/DB16708ApprovedInvestigationalCompared to alglucosidase alfa, cipaglucosidase alfa has a higher M6P content. … in Pompe disease.
ATP synthase F(1) complex subunit delta, mitochondrial
go.drugbank.com/bio_entities/BE0000484TargetEnzymeHumansATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated
Polypeptides: ATP synthase F(1) complex subunit delta, mitochondrialDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
go.drugbank.com/bio_entities/BE0001298TargetAzotobacter vinelandiiThe pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
Polypeptides: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complexSynonyms: Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexATP synthase F(1) complex subunit alpha, mitochondrial
go.drugbank.com/bio_entities/BE0003840TargetHumansATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Subunit alpha, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated
Polypeptides: ATP synthase F(1) complex subunit alpha, mitochondrialActin-related protein 2/3 complex subunit 1B
go.drugbank.com/bio_entities/BE0004249TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:11741539, PubMed:9230079). … The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:11741539, PubMed:9230079).
Polypeptides: Actin-related protein 2/3 complex subunit 1BSynonyms: Arp2/3 complex 41 kDa subunitActin-related protein 2/3 complex subunit 3
go.drugbank.com/bio_entities/BE0004253TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). … The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079).
Polypeptides: Actin-related protein 2/3 complex subunit 3Synonyms: Arp2/3 complex 21 kDa subunit