Search
Danaparoid
go.drugbank.com/drugs/DB06754ApprovedWithdrawnDanaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans [A32565]. … Danaproid is used in the treatment of heparin-induced thrombocytopenia (HIT) as an off-label indication and prevention of post-operative deep venous thrombosis (DVT).
Zinc sulfate
go.drugbank.com/drugs/DB09322ApprovedInvestigationalZinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic heal...
Mixtures: Mega Min Capsules, SmofKabiven Emulsion for InfusionCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseDabrafenib
go.drugbank.com/drugs/DB08912ApprovedInvestigationalIt was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation.[L41955] It was also used for metastatic non-small cell lung cancer with the same mutation. … [L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene.[L41955]
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP2B6 InducersTrimetazidine
go.drugbank.com/drugs/DB09069ApprovedInvestigational[L33015] Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s. … Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies.
Cysteamine
go.drugbank.com/drugs/DB00847ApprovedInvestigational[L15606,L15616] In particular, cystine deposits on the eye can cause significant discomfort throughout the day and require frequent treatment with eye drops, typically every waking hour. … Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome.
Calcium glycerophosphate
go.drugbank.com/drugs/DB11264ApprovedIt is suggested that calcium glycerophosphate promotes plaque-pH buffering, elevation of plaque [DB01373] and phosphate levels and direct interaction with dental mineral [A27153].
Chloroquine
go.drugbank.com/drugs/DB00608ApprovedInvestigationalVet approvedChloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. … [A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment of COVID-19 was revoked on 15 June 2020.
Categories: Experimental Unapproved Treatments for COVID-19, P-glycoprotein inhibitorsN-alkyl ethylbenzyl dimethyl ammonium (C12-C14)
go.drugbank.com/drugs/DB11202ApprovedIt is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties. … Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities and relatively little chance for systemic absorption
Mixtures: Med-I-San, Med-I-SanBretylium
go.drugbank.com/drugs/DB01158ApprovedRecent evidence has shown that bretylium may also inhibit the Na,K-ATPase by binding to the extracellular K-site. … The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels.
Galactose
go.drugbank.com/drugs/DB11735ApprovedInvestigationalWithdrawnNevertheless, none of these ongoing studies have yet provided formal elucidation for their proposals. As a naturally occurring sugar, it may be found in a number dairy products. … Regardless, although it is predominantly used as a pathway to generate glucose fuel for the human body, galactose is involved as an ingredient in some commonly used vaccines and non-prescription products
Categories: Tests for Liver Functional Capacity