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Displaying results 1261 - 1270 of 10000 in total
  1. Drug

    Natamycin

    go.drugbank.com/drugs/DB00826
    ApprovedInvestigational

    Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. [PubChem]

    Categories: Genito Urinary System and Sex Hormones, Antifungals for Topical Use
  2. Drug

    Fidanacogene elaparvovec

    go.drugbank.com/drugs/DB16783
    ApprovedInvestigational

    Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human coagulation FIX gene that was investigated as a potential treatment for hemophilia B. … [L46691] Hemophilia B is a rare X-linked genetic disorder characterized by abnormal coagulation due to dysfunctional coagulation factor IX with a male incidence estimated to be 1 in 30,000 male births

    Categories: Complex Mixtures
  3. Drug

    Idebenone

    go.drugbank.com/drugs/DB09081
    ApprovedInvestigational

    More specifically, idebenone is thought to transfer electrons directly to complex III of the mitochondrial ETC, thereby circumventing complex I and restoring cellular energy (ATP) generation [L885]. … It is not currently approved for use by either the Food and Drug Administration (USA) or Health Canada.

  4. Drug

    Dioxybenzone

    go.drugbank.com/drugs/DB11221
    ApprovedWithdrawn

    Dioxybenzone, or benzophenone-8, is an organic compound derived from [DB01878] that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays. … Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% [L2525].

  5. Drug

    Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10584
    ApprovedInvestigational

    Mixtures: Tetanus and Diphtheria Toxoids Adsorbed for Adult Use, Dt Polio Adsorbed - Sus ImCategories: Antiinfectives for Systemic Use, Complex Mixtures
  6. Drug

    Betula occidentalis pollen

    go.drugbank.com/drugs/DB10832
    Approved

    Betula occidentalis pollen is the pollen of the Betula occidentalis plant. Betula occidentalis pollen is mainly used in allergenic testing.

    Mixtures: Treatment Set TS340826, Treatment Set TS341824
  7. Drug

    Ibrutinib

    go.drugbank.com/drugs/DB09053
    ApprovedInvestigational

    November 2013 for the treatment of mantle cell lymphoma (MCL) under accelerated approval;[L12228] however, in April 2023, the drug manufacturer withdrew the accelerated approvals for ibrutinib in the US … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials.

  8. Drug

    Carbimazole

    go.drugbank.com/drugs/DB00389
    Approved

    Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.

    Categories: Sex Hormones and Insulins
  9. Indication

    Herpes simplex of the oral-labial

    go.drugbank.com/conditions/DBCOND0024319
    Drugs: Acyclovir
    Synonyms: Herpes simplex complex
  10. Drug

    Brimonidine

    go.drugbank.com/drugs/DB00484
    ApprovedInvestigational

    Because it is oxidately stable, brimonidine is associated with fewer reports of ocular allergic reactions compared to other alpha-2 adrenergic agonists. … It is marketed under the brand name Mirvaso.[L6535] Brimonidine is the first topical treatment approved for facial erythema of rosacea.[A178978]

    Categories: Sympathomimetics Used as Decongestants