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Denosumab
go.drugbank.com/drugs/DB06643ApprovedInvestigationalJubbonti® (denosumab-bbdz)[L53058]—were approved by the FDA in March 2024 for all indications of the reference products Xgeva® and Prolia®; Both biosimilars also received marketing authorization in the EU
Products: XGEVA Solution for Injection 120 mg/vialAzilsartan medoxomil
go.drugbank.com/drugs/DB08822ApprovedInvestigationalAlthough there is no clinical significance yet determined, azilsartan medoxomil may have potential off-label uses in patients with a history of myocardial infarction or heart failure.[A232863]
Mirfentanil
go.drugbank.com/drugs/DB09175ExperimentalMirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor.
Human Menstrual Blood-derived Stem Cells
go.drugbank.com/drugs/DB15738InvestigationalStem cells are self-renewing and proliferate without differentiation, with the two major groups being embryonic stem cells (ESCs) and adult stem cells (ASC). Differentiation occurs under different conditions into different cell types. ES...
Ceramide NP
go.drugbank.com/drugs/DB14111InvestigationalCeramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. … Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid) [A27233]. It is widely used as a moisturizer in various cosmetic and personal products.
Synonyms: Ceramide NP, N-oleoylphytosphingosineEthylmorphine
go.drugbank.com/drugs/DB01466IllicitInvestigationalIt is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world.
Foreskin keratinocyte (neonatal)
go.drugbank.com/drugs/DB10772ApprovedSkin, the largest organ of the human body, plays the main role in protecting the body from mechanical damage. It is composed of epidermal, dermal and hypodermal layers. The barrier function of the skin owed to its avascular epidermal lay...
Amivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigationalAmivantamab, also known as JNJ-61186372, is an anti-EGFR-MET bispecific antibody, derived from Chinese hamster ovary cells, approved for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCL...
Casimersen
go.drugbank.com/drugs/DB14984ApprovedInvestigationalDuchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive impairment of ambulatory, pulmonary, and cardiac function and is invariably ...
N-Acetylglucosamine
go.drugbank.com/drugs/DB00141ApprovedInvestigationalNutraceuticalThe N-acetyl derivative of glucosamine.
Synonyms: N-Acetylchitosamine, N-Acetylglucosamine