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Polyinosinic-polycytidylic acid
go.drugbank.com/drugs/DB16467InvestigationalSalts: Polyinosinic polycytidylic acid sodium saltCategories: Experimental Unapproved Treatments for COVID-19Nifuroxazide
go.drugbank.com/drugs/DB13855InvestigationalMixtures: METRO FORTProducts: DIAFURYL FORT 200 MG KAPSÜL, 16 ADET, DIAFURYL FORT 200 MG KAPSÜL, 24 ADETSotorasib
go.drugbank.com/drugs/DB15569ApprovedInvestigational[L34288] This mutation makes up >50% of all KRAS mutations.[A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s. … [A187547] The drug [MRTX849] is also currently being developed and has the same target.
CX-052075
go.drugbank.com/drugs/DB31655Approved[L53413,A274083] mNEXSPIKE was approved by the US FDA in June 2025 for use in patients who have been previously vaccinated with any COVID-19 vaccine and who are at a higher risk of severe outcomes from … [L53408,L53423] The original approval was formulated with the JN.1 strain ([mRNA-1283]), but was ultimately updated to the sublineage LP.8.1.[L54586]
Maribavir
go.drugbank.com/drugs/DB06234ApprovedInvestigationalMaribavir was approved by the FDA in November 2021, under the name Livtencity (Takeda), for the treatment of resistant CMV infections in post-transplant patients. … [L39327] The drug was also approved by Health Canada in September 2022 [L43262] and by European Commission in November 2022.[L44411]
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTelmisartan
go.drugbank.com/drugs/DB00966ApprovedInvestigationalTelmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinit...
Categories: Antihypertensive Agents Indicated for HypertensionProducts: Semintra 4mg/ml Oral Solution for CatsChlormerodrin
go.drugbank.com/drugs/DB00534ApprovedWithdrawnThe radiolabeled form has been used as a diagnostic and research tool. It is no longer used and has been replaced with new classes of diuretic drugs.
Aluminum sulfate
go.drugbank.com/drugs/DB11239ApprovedBy overcoming the body barriers, Al may infiltrate into the blood and lead to toxic effects in liver, bone and the central nervous system [L2145]. … It is a chemical agent used in water purification, the pH regulation of garden soil, and other commercial or industrial applications.
Birch bark extract
go.drugbank.com/drugs/DB16536ApprovedInvestigational[L42390] Filsuvez was subsequently approved for the same indication by the US FDA in December 2023. … [A249945] Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used for production are _Betula pendula_ Roth (silver birch) and _Betula pubescens_ Ehrh
Sezary Syndrome
go.drugbank.com/conditions/DBCOND0001518Synonyms: Cutaneous T-cell lymphoma, no International Classification of Diseases for Oncology subtype