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Tafluprost
go.drugbank.com/drugs/DB08819ApprovedChemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012. … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.
Mixtures: Taptiqom 15 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis, TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose containerNaltrexone
go.drugbank.com/drugs/DB00704ApprovedInvestigationalVet approvedDerivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. … The FDA has approved naltrexone for the treatment of alcohol dependence.
Categories: Heterocyclic Compounds with 4 or More Rings, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: NARPAN TABLET 50 mg, ReVia 50 mg FilmtablettenFelodipine
go.drugbank.com/drugs/DB01023ApprovedIn addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent … It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
Mixtures: DELIX DUO 2.5 MG/2.5 MG TABLET, 30 ADET, DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADETProducts: MODIP 5 MG, MODIP 10 MGLumefantrine
go.drugbank.com/drugs/DB06708ApprovedInvestigationalThis combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp.
Mixtures: Riamet 20 mg/120 mg - Tabletten, ARTEMETERO 20 MG + LUMEFANTRINA 120 MG TABLETAPatisiran
go.drugbank.com/drugs/DB14582ApprovedPatisiran is a first in class short interfering RNA for the treatment of patients with polyneuropathy caused by hereditary transthyretin-mediated amyloidosis [L4220]. … The approval for Onpattro was granted to Alnylam Pharmaceuticals, Inc. in August of 2018. Onpattro has been granted Fast Track, Priority Review and Breakthrough Therapy, and Orphan Drug designations.
Categories: Compounds used in a research, industrial, or household settingCipepofol
go.drugbank.com/drugs/DB16295ApprovedInvestigationalregulatory history outside the United States: China's National Medical Products Administration approved it in December 2020 under the trade name Sishuning, and its Chinese label has since expanded to cover … of anesthetics while reducing the injection pain and respiratory depression that have long been recognized as limitations of intravenous anesthesia.
Calcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers. … Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent.
Mixtures: OQ-BALANS, OQ-BALANSPotassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnThe FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release … A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
Synonyms: Chloride of potash, Muriate of potashMixtures: OQ-BALANS, OQ-BALANSCyclothiazide
go.drugbank.com/drugs/DB00606ApprovedIt is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. … The antihypertensive mechanism of cyclothiazide is less well understood although it may be mediated through its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance
Categories: combinations of sulfonamidesBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigational[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. … [A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such
Mixtures: CONCOR ® AM 5 MG / 10 MG, Concor AM 5 mg/5 mg TabletsProducts: Nu-bisoprolol, TABLETS 5 MG