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Displaying results 1281 - 1290 of 10000 in total
  1. Drug

    Isoprenaline

    go.drugbank.com/drugs/DB01064
    ApprovedInvestigational

    Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion … [A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and cardiac output, without vasoconstriction

    Synonyms: N-Isopropylnoradrenaline, N-IsopropylnorepinephrineInternational brands: Proternol L
  2. Drug

    Dexamethasone

    go.drugbank.com/drugs/DB01234
    ApprovedInvestigationalVet approved

    [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms … Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic

    Synonyms: 16α-Methyl-9α-fluoro-1-dehydrocortisol, 1-Dehydro-16α-methyl-9α-fluorohydrocortisoneMixtures: LERGOSIN-A, BAYCUTEN N
  3. Drug

    Levomenthol

    go.drugbank.com/drugs/DB00825
    ApprovedInvestigational

    Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. … Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration

    Synonyms: (1R-(1-α,2-β,5-α))-5-methyl-2-(1-methylethyl)cyclohexanol, CYCLOHEXANOL, 5-METHYL-2-(1-METHYLETHYL)-, (1R-(1.ALPHA.,2.BETA.,5.ALPHA.))-Mixtures: Burn Relief Gel, Burn Relief Cream
  4. Drug

    Exenatide

    go.drugbank.com/drugs/DB01276
    ApprovedInvestigational

    Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. … [L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension, was discontinued in 2021.

    Categories: Drugs Used in Diabetes, Glucagon-like peptide-1 (GLP-1) analoguesSynonyms: Exendin 4, Exendin-4
  5. Drug

    Benzydamine

    go.drugbank.com/drugs/DB09084
    ApprovedInvestigational

    Moreover, unlike aspirin-like NSAIDs which are acids or metabolised to acids, benzydamine is in fact a weak base. … Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties

    Mixtures: KLOROBEN FORT 3 MG/ML+ 2 MG/ML GARGARA, 200 ML, KLOROBEN FORT 3 MG/ML+ 2 MG/ML ORAL SPREY, 40 MLCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-Ring
  6. Indication

    Conditions where a reduction of gastric acid secretion is required

    go.drugbank.com/conditions/DBCOND0117234
    Drugs: Pantoprazole
    Synonyms: Conditions where a reduction of gastric acid secretion is required
  7. Drug

    Bisacodyl

    go.drugbank.com/drugs/DB09020
    ApprovedInvestigational

    Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. … [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]

    Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, Dyrax-Q TabSynonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)
  8. Target

    Pleckstrin homology domain-containing family A member 4

    go.drugbank.com/bio_entities/BE0001278
    TargetHumans

    Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides

    Polypeptides: Pleckstrin homology domain-containing family A member 4Synonyms: PH domain-containing family A member 4
  9. Target

    Pleckstrin homology domain-containing family A member 1

    go.drugbank.com/bio_entities/BE0003262
    TargetHumans

    Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane

    Polypeptides: Pleckstrin homology domain-containing family A member 1Synonyms: PH domain-containing family A member 1
  10. Target

    Potassium voltage-gated channel subfamily A member 4

    go.drugbank.com/bio_entities/BE0004502
    TargetHumans

    In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes, making it difficult to assign currents observed in intact tissues to any particular potassium channel family member … Homotetrameric KCNA4 forms a potassium channel that opens in response to membrane depolarization, followed by rapid spontaneous channel closure (PubMed:19912772, PubMed:8495559).

    Polypeptides: Potassium voltage-gated channel subfamily A member 4