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Displaying results 121 - 130 of 453 in total
  1. Target

    Fatty acid-binding protein, adipocyte

    go.drugbank.com/bio_entities/BE0001194
    CarrierTargetHumans

    Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus

    Polypeptides: Fatty acid-binding protein, adipocyteSynonyms: Fatty acid-binding protein 4, Adipocyte-type fatty acid-binding protein
  2. Target

    Cyclopropane mycolic acid synthase 2

    go.drugbank.com/bio_entities/BE0001211
    TargetMycobacterium tuberculosis

    Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via … In the absence of MmaA2, CmaA2 has a non-specific cis-cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic

    Polypeptides: Cyclopropane mycolic acid synthase 2Synonyms: Cyclopropane fatty acid synthase, Mycolic acid methyltransferase
  3. Target

    Fatty acid metabolism regulator protein

    go.drugbank.com/bio_entities/BE0001383
    TargetShigella flexneri

    Multifunctional regulator of fatty acid metabolism.

    Polypeptides: Fatty acid metabolism regulator protein
  4. Target

    Excitatory amino acid transporter 4

    go.drugbank.com/bio_entities/BE0002270
    TargetHumans

    Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:7791878). … Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:26690923, PubMed:7791878).

    Polypeptides: Excitatory amino acid transporter 4
  5. Target

    Cyclopropane mycolic acid synthase MmaA2

    go.drugbank.com/bio_entities/BE0002512
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. … Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence.

    Polypeptides: Cyclopropane mycolic acid synthase MmaA2Synonyms: Mycolic acid methyltransferase
  6. Target

    Nogalonic acid methyl ester cyclase

    go.drugbank.com/bio_entities/BE0003204
    TargetStreptomyces nogalater

    Catalyzes the formation of nogalaviketone from nogalonic acid methyl ester (NAME), the last ring-closure step in the biosynthesis of nogalamycin.

    Polypeptides: Nogalonic acid methyl ester cyclase
  7. Target

    Free fatty acid receptor 4

    go.drugbank.com/bio_entities/BE0003399
    TargetHumans

    Consequently stimulates fatty acid uptake and oxidation in mitochondria together with UCP1-mediated thermogenic respiration, eventually reducing fat mass (By similarity). … Mediates LCFAs inhibition of GHRL secretion, an appetite-controlling hormone (By similarity). In taste buds, contributes to sensing of dietary fatty acids by the gustatory system (By similarity).

    Polypeptides: Free fatty acid receptor 4Synonyms: Omega-3 fatty acid receptor 1
  8. Target

    Fatty acid-binding protein, intestinal

    go.drugbank.com/bio_entities/BE0003591
    CarrierTargetHumans

    FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. … Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids.

    Polypeptides: Fatty acid-binding protein, intestinalSynonyms: Fatty acid-binding protein 2, Intestinal-type fatty acid-binding protein
  9. Target

    Ileal sodium/bile acid cotransporter

    go.drugbank.com/bio_entities/BE0003643
    TransporterTargetHumans

    Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling … Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate (PubMed:7592981, PubMed:9458785, PubMed:9856990).

    Polypeptides: Ileal sodium/bile acid cotransporterSynonyms: Ileal Na(+)/bile acid cotransporter, Apical sodium-dependent bile acid transporter
  10. Target

    Alpha-1-acid glycoprotein 2

    go.drugbank.com/bio_entities/BE0003663
    TargetHumans

    Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction

    Polypeptides: Alpha-1-acid glycoprotein 2