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Trimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approvedTrimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it … [L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of
Synonyms: 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine, 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamineMixtures: EUSAPRIM E SUSPENS F ERW, TRIMETOPRIMA 40 MG/5 ML SULFAMETOXAZOL 200MG/5 ML SUSPENSIONTiaprofenic acid
go.drugbank.com/drugs/DB01600ApprovedTiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain.
Categories: Non COX-2 selective NSAIDSSynonyms: 2-(5-Benzyl-2-thienyl)propionsäure, 2-(5-Benzoyl-thiophen-2-yl)-propionic acidMethylchloroisothiazolinone
go.drugbank.com/drugs/DB14197ApprovedMethylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties. … It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area.
Synonyms: 5-Chloro-N-methylisothiazolin-3-one, 4-Isothiazolin-3-one, 5-chloro-2-methyl-Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingOlesoxime
go.drugbank.com/drugs/DB05185InvestigationalOlesoxime is a cholesterol-like small molecule that has demonstrated a remarkable neuroprotective profile in a battery of both in vitro and in vivo preclinical models.
Synonyms: (EZ)-N-(CHOLEST-4-EN-3-YLIDENE)HYDROXYLAMINE, cholest-4-en-3-one, oximeMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalAlthough demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent … An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022].
Synonyms: m-Aminosalicylic acid, 5-ASAProducts: MESALAZINA EG, MESALAZINA EG STADASulfamethoxazole
go.drugbank.com/drugs/DB01015ApprovedInvestigationalSulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. … [L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps
Mixtures: EUSAPRIM E SUSPENS F ERW, TRIMETOPRIMA 40 MG/5 ML SULFAMETOXAZOL 200MG/5 ML SUSPENSIONCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … [L7423] Losartan was granted FDA approval on 14 April 1995.[L7423]
Synonyms: 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole, (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanolMixtures: ARAMAX ® 5/50 MG TABLETAS, ARAMAX ® 5/50 MG CAPSULASProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedA low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609]. … Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy.
Synonyms: (S)-Pregn-4-en-3,20-dione, Pregn-4-ene-3,20-dioneMixtures: Minoxidil 5% / Progesterone 0.1% / Tretinoin 0.025%, SYNERGAL® DOBLESulfaphenazole
go.drugbank.com/drugs/DB06729ApprovedSulfaphenazole is a sulfonamide antibacterial.
Synonyms: N'-(1-phenylpyrazol-5-yl)sulfanilamide, N(1)-(1-phenylpyrazol-5-yl)sulfanilamideCategories: Cytochrome P-450 CYP2B6 Inhibitors, Heterocyclic Compounds, 1-RingEthotoin
go.drugbank.com/drugs/DB00754ApprovedEthotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: (±)-3-ethyl-5-phenylhydantoin, 3-ethyl-5-phenylhydantoin