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Displaying results 121 - 130 of 8044 in total
  1. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    [A39075] Ibuprofen was finally patented in 1961 and this drug was first launched against rheumatoid arthritis in the UK in 1969 and USA in 1974. It was the first available over-the-counter NSAID. … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin.

    Mixtures: FORT-GRIP, Period Pills by BiikayCategories: Topical Products for Joint and Muscular Pain, Experimental Unapproved Treatments for COVID-19
  2. Target

    Copper chaperone for superoxide dismutase

    go.drugbank.com/bio_entities/BE0005815
    CarrierTargetHumans

    Delivers copper to copper zinc superoxide dismutase (SOD1)

    Polypeptides: Copper chaperone for superoxide dismutase
  3. Target

    Receptor for retinol uptake STRA6

    go.drugbank.com/bio_entities/BE0009879
    TransporterHumans

    Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid (PubMed:18316031). … Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein

    Polypeptides: Receptor for retinol uptake STRA6
  4. Drug

    Glycerin

    go.drugbank.com/drugs/DB09462
    ApprovedInvestigational

    A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.

    Mixtures: Sterile Diluent for Allergenic Extract, Clear Eyes for Dry EyesCategories: Drugs for Constipation, Compounds used in a research, industrial, or household setting
  5. Drug

    Salicylic acid

    go.drugbank.com/drugs/DB00936
    ApprovedInvestigationalVet approved

    A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions.

    Mixtures: Pimplepatch By Glam Up, Aveeno favorites from clear complexionCategories: Antifungals for Topical Use, Antifungals for Dermatological Use
  6. Drug

    Asparaginase Escherichia coli

    go.drugbank.com/drugs/DB00023
    ApprovedInvestigational

    Asparaginase derived from _Escherichia coli_ (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia … Therapeutic L-asparaginase from _E. coli_ works by depleting the levels of non-essential amino acid, asparagine, in lymphoblastic leukemic cells thus promoting apoptotic cell death [A31999].

    Products: LEUNASE FOR INJECTION 10,000 iu/vial, KIDROLASE 10000 UI
  7. Drug

    Benzylpenicillin

    go.drugbank.com/drugs/DB01053
    ApprovedInvestigationalVet approved

    Natural penicillins are considered the drugs of choice for several infections caused by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, B, C and G streptococci … Aminoglycosides may be added for synergy against group B streptococcus (*S. agalactiae*), *S. viridans*, and *Enterococcus faecalis*.

    Mixtures: PENCAIN K-400 İ.Ü. ENJEKTABL FLAKON, 1 FLAKON + 1 AMPUL, PENCAIN K-800 İ.Ü. IM ENJEKTABL FLAKON, 1 FLAKON + 1 AMPULCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  8. Drug

    Bemiparin

    go.drugbank.com/drugs/DB09258
    ApprovedWithdrawn

    Interestingly, current research is underway for the potential benefit of bemiparin in the treatment of tumors and diabetic foot ulcers [L1468, A7866]. … These heparins have lower anti-thrombin activity than the traditional low molecular weight heparins and act mainly on factor-Xa, reducing the risk of bleeding due to selectivity for this specific clotting

    Products: HIBOR® 3.500 UI., HIBOR® 10.000 UI
  9. Drug

    Romiplostim

    go.drugbank.com/drugs/DB05332
    ApprovedInvestigational

    The peptibody molecule has two identical single-chain subunits, each one is made up of 269 amino acid residues. … Romiplostim is produced by recombinant DNA technology in Escherichia coli. FDA approved on August 22, 2008.

    Products: ROMIPLATE POWDER FOR SOLUTION FOR INJECTION 250 ?g/vial, ROMIPLATE 250 ug INJECTION
  10. Drug

    Vigabatrin

    go.drugbank.com/drugs/DB01080
    ApprovedInvestigational

    [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its US approval by the FDA in 2009 mandated the creation of a drug registry to monitor patients for visual … [L13616] It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA.

    Products: SABRIL 500 MG 50 SASE, Vigabatrin for Oral Solution