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Antithymocyte immunoglobulin (rabbit)
go.drugbank.com/drugs/DB00098ApprovedInvestigationalThymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. … Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.
Categories: Fluids and Secretions, Amino Acids, Peptides, and ProteinsProducts: THYMOGLOBULINE 5MG/ML, Thymoglobuline 5mg/ml Powder for concentrate for solution for infusionAvalglucosidase alfa
go.drugbank.com/drugs/DB16099ApprovedInvestigationalGAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. … Pompe disease is characterized by progressive muscle weakness and loss of motor function, including respiratory muscle weakness, which leads to premature death and debilitating effects on people’s lives
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismProducts: NEXVIAZYME 100mg Powder for Concentrate for Solution for InfusionDimercaprol
go.drugbank.com/drugs/DB06782ApprovedIt was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. … Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects.
Categories: Compounds used in a research, industrial, or household settingInternational brands: Bal In Oil InjectionGallium citrate Ga-67
go.drugbank.com/drugs/DB06784ApprovedAlthough the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation … Ga-67 scintigraphy (GS) cannot differentiate between tumor and acute inflammation. [NCI Thesaurus]
Categories: Inflammation and Infection DetectionProducts: GALLIUM CITRATE (GA67) INJ 37 MBQ/ML (82 MBQ), GALLIUM CITRATE (GA67) INJ 37 MBQ/ML (123 MBQ)Ifosfamide
go.drugbank.com/drugs/DB01181ApprovedInvestigationalIfosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.
Mixtures: IFEX and MESNEX, IFEX and MESNEXCategories: Antineoplastic and Immunomodulating AgentsDiethylcarbamazine
go.drugbank.com/drugs/DB00711ApprovedInvestigationalVet approvedWithdrawnAn anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Categories: Piperazine and Derivatives, Antiparasitic Products, Insecticides and RepellentsProducts: Hetrazan Tab 50mgVindesine
go.drugbank.com/drugs/DB00309ApprovedInvestigationalWithdrawnMajor side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Categories: Antineoplastic and Immunomodulating AgentsProducts: Eldisine Inj 5mg/2mlRisedronic acid
go.drugbank.com/drugs/DB00884ApprovedInvestigationalIt functions by preventing resorption of bone[FDA Label][A959]. … Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Mixtures: RICAVIS 6MG/1000MG/880IU EFERVASAN TABLET, 28 ADET, RISEPLUS D3 35 MG/5600 IU EFERVESAN TABLET, 4 ADETCategories: Calcium-Regulating Hormones and Agents, risedronic acid and colecalciferolMagnesium chloride
go.drugbank.com/drugs/DB09407ApprovedInvestigationalMagnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Mixtures: Aminosyn II and Dextrose, Plasma-Lyte 148 and dextroseCategories: Alimentary Tract and Metabolism, Blood and Blood Forming OrgansHydrocortisone acetate
go.drugbank.com/drugs/DB14539ApprovedInvestigationalVet approvedMixtures: Anodan-HC 10mg Suppositories, CORTIGRA-NCategories: Hydrocortisone and derivatives, Hormones, Hormone Substitutes, and Hormone Antagonists