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Displaying results 1301 - 1310 of 2828 in total
  1. Drug

    Estetrol

    go.drugbank.com/drugs/DB12235
    ApprovedInvestigational

    Naturally or synthetically produced steroid estrogens have a wide range of pharmaceutical uses ranging from hormonal contraception to the treatment of menopausal symptoms. Estetrol (E4) is a native estrogen occurring naturally during pre...

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  2. Drug

    Nelotanserin

    go.drugbank.com/drugs/DB12555
    Investigational

    It increases non-REM sleep, the most restorative phase of the sleep cycle, without sacrificing REM or dream sleep. … Nelotanserin has been used in trials studying the treatment of Lewy Body Dementia, Visual Hallucinations, Dementia With Lewy Bodies, and REM Sleep Behavior Disorder.

  3. Drug

    Quinagolide

    go.drugbank.com/drugs/DB09097
    ApprovedWithdrawn

    Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility a...

    Categories: Genito Urinary System and Sex Hormones
  4. Drug

    Rufinamide

    go.drugbank.com/drugs/DB06201
    Approved

    Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.

    Categories: Membrane Transport Modulators
  5. Drug

    NSI-566

    go.drugbank.com/drugs/DB17954
    Investigational

    NSI-566 is a stem cell therapy consisting of human spinal cord-derived neural stem cells.

  6. Target

    ATP-binding cassette sub-family C member 2

    go.drugbank.com/bio_entities/BE0001069
    TargetTransporterHumans

    ATP-dependent transporter of the ATP-binding cassette (ABC) family that hydrolyzes ATP to enable active transport of substrates conjugated with glucuronate, glutathione or sulfate. … Displays selective transporter activity toward sulfated conjugates, transports sulfated bile salts such as taurolithocholate sulfate but is inactive toward androgen sulfates (PubMed:16332456, PubMed:39993711

    Synonyms: Canalicular multispecific organic anion transporter 1Function: ABC-type glutathione S-conjugate transporter activity
  7. Drug

    Stem-cell derived exosome vesicle products

    go.drugbank.com/drugs/DB15743
    Experimental

    While many contain a conserved set of proteins, they also carry unique tissue type-specific proteins. … Mesenchymal stem cells (MSCs) exert their therapeutic effects through multiple modalities, including paracrine factors such as exosomes.

    Synonyms: Stem-cell derived exosome vesicles, Stem-cell derived extracellular vesicles
  8. Drug

    OSSM-007

    go.drugbank.com/drugs/DB18553
    Experimental

    OSSM-007 consists of interferon-gamma primed allogeneic mesenchymal stem cells.

  9. Drug

    Dilanubicel

    go.drugbank.com/drugs/DB18722
    Investigational

    Dilanubicel consists of ex vivo expanded hematopoietic stem and progenitor cells.

  10. Drug

    Etonogestrel

    go.drugbank.com/drugs/DB00294
    ApprovedInvestigational

    Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and F...

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System