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Displaying results 1301 - 1310 of 10000 in total
  1. Drug

    Fluticasone propionate

    go.drugbank.com/drugs/DB00588
    ApprovedInvestigational

    Fluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label].

    Mixtures: FLUTIFORM® 250 MCG / 10 MCG, FLUTIFORM® 250 MCG / 10 MCGCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  2. Drug

    Hydroxychloroquine

    go.drugbank.com/drugs/DB01611
    ApprovedInvestigational

    [A183092] Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV-2. … [L14312]** Hydroxychloroquine was granted FDA approval on 18 April 1955.[L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546]

    Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsSynonyms: 7-chloro-4-[5-(N-ethyl-N-2-hydroxyethylamino)-2-pentyl]aminoquinoline, 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline
  3. Drug

    Vepdegestrant

    go.drugbank.com/drugs/DB19006
    ApprovedInvestigational

    [L56181] It is indicated for the treatment of adults with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, and ESR1-mutated advanced or metastatic breast cancer … [A275508, A275509] On May 1, 2026, the FDA granted approval for vepdegestrant tablets under the trade name VEPPANU.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: 2,6-piperidinedione, 3-(1,3-dihydro-1-oxo-5-(4-((1-(4-((1r,2s)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl)phenyl)-4-piperidinyl)methyl)-1-piperazinyl)-2h-isoindol-2-yl)-, (3s)-
  4. Drug

    Furvina

    go.drugbank.com/drugs/DB16547
    Experimental

    Furvina is marketed in Cuba as Dermofural®, an ointment containing G1 as the only active principle ingredient. It is used to treat dermatological infections.[A228063]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(5-Bromofur-2-yl)-2-bromo-2-nitroethene, 2-Bromo-5-(2-bromo-2-nitrovinyl)furan
  5. Drug

    Riboflavin tetrabutyrate

    go.drugbank.com/drugs/DB14727
    Investigational

    Synonyms: Riboflavin 2',3',4',5'-tetrabutyrate, Riboflavin, 2',3',4',5'-tetrabutanoateCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-Ring
  6. Drug

    APL-030

    go.drugbank.com/drugs/DB18735
    Experimental

    APL-030 is a orally-active small molecule inhibitor of GCN2.

    Synonyms: N-(4-((2-aminopyrimidin-5-yl)ethynyl)-3-fluoropyridin-2-yl)-5-chloro-2-methoxypyridine-3-sulfonamide
  7. Drug

    Denifanstat

    go.drugbank.com/drugs/DB17576
    Investigational

    Due to its antineoplastic activities, it is being investigated for various cancers.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Benzonitrile, 4-(1-(4-cyclobutyl-2-methyl-5-(3-methyl-1h-1,2,4-triazol-5-yl)benzoyl)-4-piperidinyl)-
  8. Drug

    Baclofen

    go.drugbank.com/drugs/DB00181
    ApprovedInvestigational

    Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977.

    Mixtures: Innoprax-5Categories: GABA-B Receptor Agonists
  9. Drug

    Rivastigmine

    go.drugbank.com/drugs/DB00989
    ApprovedInvestigational

    Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. … Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate, (S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate
  10. Drug

    Tricyclazole

    go.drugbank.com/drugs/DB02891
    Investigational

    Synonyms: 5-methyl-1,2,4-triazolo(3,4-b)benzothiazole, 5-methyl-1,2,4-triazolo(3,4-b)(1,3)benzothiazoleCategories: Heterocyclic Compounds, 1-Ring