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Clodronic acid
go.drugbank.com/drugs/DB00720ApprovedInvestigationalVet approvedClodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid]. … [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification.
2,2'-Dibenzothiazyl disulfide
go.drugbank.com/drugs/DB14201Approved2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic rubber and plastic regeneration. It is also a known allergen and dermatological sensitizer. … Sensitivity to 2,2'-Dibenzothiazyl disulfide may be identified with a clinical patch test.
Hydroxycitronellal
go.drugbank.com/drugs/DB14187ApprovedHydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and as a result commercially available products are restricted by the International Fragrance Association (IFRA) to contain … Hydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products such as deodorants, soaps, antiseptics, and other household items.
Synonyms: 3,7-dimethyl-7-hydroxyoctan-1-alLotiglipron
go.drugbank.com/drugs/DB21631InvestigationalLotiglipron is under investigation in clinical trial NCT05579977 (Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People … Lotiglipron has a monoisotopic molecular weight of 574.2 Da.
Baricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigationalBaricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. … Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexFactor XIII (human)
go.drugbank.com/drugs/DB12909ApprovedInvestigationalWithin the body, FXIII circulates as a heterotetramer composed of 2 A-subunits and 2 B-subunits (A2B2)[A32363]. … Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation
International brands: Fibrogammin PBicisate
go.drugbank.com/drugs/DB11164ApprovedBicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. … [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved on November 23, 1994.[L2029]
Products: MON.ECD KIT 1 MG IV ENJEKSİYON İÇİN LİYOZFİLİZE TOZ İÇEREN FLAKON, 2 ADETPropiolactone
go.drugbank.com/drugs/DB09348ApprovedWithdrawnPropiolactone is a lactone compound with a four-membered ring. It is a colorless liquid with a pungent slightly sweet odor. … [A32144] It is currently FDA approved for its use as an indirect additive used in food contact substances. Propiolactone was first commercially available in the United States in 1958.[A32144]
Categories: Compounds used in a research, industrial, or household settingFuraprevir
go.drugbank.com/drugs/DB12785InvestigationalFuraprevir is under investigation in clinical trial NCT01523990 (A Study to Evaluate the Safety, Tolerability, and PK in Healthy Volunteers and HCV Genotype 1 Infected Patients).
Dirocaftor
go.drugbank.com/drugs/DB16143InvestigationalDirocaftor is under investigation in clinical trial NCT03251092 (Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis).