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Empagliflozin
go.drugbank.com/drugs/DB09038ApprovedInvestigational[A203501] Attempts at overcoming these limitations first saw the development of O-glucoside analogs of phlorizin (e.g. … Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney.
Clidinium
go.drugbank.com/drugs/DB00771ApprovedIt is used for the treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome. … Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract.
Pargyline
go.drugbank.com/drugs/DB01626ApprovedPargyline is a monoamine oxidase inhibitor with antihypertensive properties.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeCefotaxime
go.drugbank.com/drugs/DB00493ApprovedInvestigationalIn most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Products: CEFOTAXIME MYLAN GENERICS, CEFOTAXIME SIGMA TAU GENERICSPolyethylene glycol 300
go.drugbank.com/drugs/DB11161ApprovedLow molecular weight glycols are observed to exhibit antibacterial properties as well. PEG 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes. … Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries.
Tolnaftate
go.drugbank.com/drugs/DB00525ApprovedVet approvedIt may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Synonyms: O-2-Naphthyl m,N-dimethylthiocarbanilate, m,N-Dimethylthiocarbanilic acid O-2-naphthyl esterProducts: NAFTATE CREAM 1% w/w, TINALITE CREAM 1% w/wVirginiamycin M1
go.drugbank.com/drugs/DB01669ExperimentalPristinamycin IIA is a macrolide antibiotic, a member of the streptogramin A group of antibiotics, and one component of pristinamycin. It is produced by Streptomyces graminofaciens and other bacteria.
Filgrastim
go.drugbank.com/drugs/DB00099ApprovedInvestigationalIt is also used to manage severe chronic neutropenia and mobilize hematopoietic progenitor cells to the peripheral blood for collection by leukapheresis in patients undergoing peripheral blood progenitor … Filgrastim mimics the biological actions of G-CSF to increase the levels of neutrophils in the blood.
Products: ZARZIO® 30 MU/0.5 ML SOLUCION INYECTABLE O PARA PERFUSION EN JERINGA PRECARGADAConjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigationalBoth of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble. … However, until 1986 official clinical trials were performed and this product was determined to be effective for the treatment of osteoporosis.
Lithium cation
go.drugbank.com/drugs/DB01356ApprovedInvestigationalWithdrawnLithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. … Lithium can also be used to augment other antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome