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Displaying results 1311 - 1320 of 10000 in total
  1. Target

    Band 3 anion transport protein

    go.drugbank.com/bio_entities/BE0012390
    TransporterTargetHumans

    Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine (PubMed:10926824, PubMed:14734552, PubMed:16227998, PubMed:24121512, PubMed:28387307)

    Synonyms: DI
  2. Indication

    Otoferlin Gene-mediated Hearing Loss

    go.drugbank.com/conditions/DBCOND0170571
    Drugs: Lunsotogene parvec
    Synonyms: Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF)
  3. Indication

    Polyneuropathies

    go.drugbank.com/conditions/DBCOND0030109
    Drugs: Vutrisiran
    Synonyms: Other neurologic disorders in Lyme disease
  4. Indication

    Elevation of serum triglyceride levels

    go.drugbank.com/conditions/DBCOND0097366
    Drugs: Atorvastatin · Lovastatin · Pitavastatin · Pravastatin
    Synonyms: Increases in triglycerides, Increase in blood triglycerides
  5. Drug

    Methyldopa

    go.drugbank.com/drugs/DB00968
    ApprovedInvestigational

    [A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. … [A232224] First introduced in 1960 as an antihypertensive agent, methyldopa was considered to be useful in certain patient populations, such as pregnant women and patients with renal insufficiency.

    Products: Aldomet Ester HCl Inj
  6. Drug

    Ambrisentan

    go.drugbank.com/drugs/DB06403
    ApprovedInvestigational

    Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. … In addition, it is approved in the United States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and to improve exercise ability.

    Products: AMBRISENTAN DR. REDDY?S
  7. Target

    Interferon-inducible protein AIM2

    go.drugbank.com/bio_entities/BE0011287
    TargetHumans

    Inflammasomes are supramolecular complexes that assemble in the cytosol in response to pathogens and other damage-associated signals and play critical roles in innate immunity and inflammation (PubMed: … Also acts as a regulator of neurodevelopment via its role in the DNA damage response: acts by promoting neural cell death in response to DNA damage in the developing brain, thereby purging genetically

    Synonyms: Absent in melanoma 2
  8. Drug

    Magnesium chloride

    go.drugbank.com/drugs/DB09407
    ApprovedInvestigational

    Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

    Mixtures: INYECCION MULTIPLE DE ELECTROLITOS TIPO I, Amino Acid InJ.W.elecw.25%dex
  9. Drug

    Conjugated estrogens

    go.drugbank.com/drugs/DB00286
    ApprovedInvestigational

    [T475] The conjugated estrogen mixture was approved for marketing in US in 1942 based on the efficacy against certain conditions. … Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.

    Products: Premarin Inj 25mg/5ml
  10. Drug

    Silver cation

    go.drugbank.com/drugs/DB14521
    Investigational

    Mixtures: Silver Ion Antibacterial Gel, Antibacterial hand washing gelSynonyms: Silver, ion (Ag1+)