Search
Nuclear factor NF-kappa-B p105 subunit
go.drugbank.com/bio_entities/BE0001086TargetHumansNF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … the enhancer region of genes involved in immune response and acute phase reactions.
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Irbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigational[L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy. … [L7459] Unlike angiotensin converting enzyme inhibitors, ARBs are not associated with a dry cough.[L7456,L7459] Irbesartan was granted FDA approval on 30 September 1997.[L7456,L7459]
Mixtures: IRBESARTAN/HCT AL 300/25, IRBESARTAN/HCT AL 300/25Categories: Angiotensin II receptor antagonists, Angiotensin II Type 2 Receptor BlockersBiotin
go.drugbank.com/drugs/DB00121ApprovedInvestigationalNutraceuticalA water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Mixtures: Multi II IV Vi Tab, Vc IISynonyms: D-Biotin, D-(+)-biotinSodium citrate
go.drugbank.com/drugs/DB09154ApprovedInvestigationalIt is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. … From the medical point of view, it is used as alkalinizing agent. It works by neutralizing excess acid in the blood and urine. It has been indicated for the treatment of metabolic acidosis.
Mixtures: A-C-D Solution, DONEXAN DXCategories: Compounds used in a research, industrial, or household setting, Miscellaneous GI DrugsNorfloxacin
go.drugbank.com/drugs/DB01059ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Categories: Topoisomerase II InhibitorsProducts: NORFLOXACINA DR. REDDY'S, NORFLOXACIN AL 400MGInositol
go.drugbank.com/drugs/DB13178ApprovedInvestigationalWithdrawnIt is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin because even though its presence is vital in the body, a deficiency in this molecule does not translate … Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol.
Mixtures: Multi II IV Vi Tab, Multipack IISynonyms: L-myo-InositolChlorprothixene
go.drugbank.com/drugs/DB01239ApprovedInvestigationalWithdrawnChlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class. … Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.
Categories: Dopamine D2 Receptor AntagonistsNuclear factor NF-kappa-B complex
go.drugbank.com/bio_entities/BE0009554TargetHumansNF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family.
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Thiocolchicoside
go.drugbank.com/drugs/DB11582InvestigationalIt is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.[L1663] … Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of _Superba gloriosa_.
Products: KENFIX 4 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 6 AMPUL, KEYRELAKS 4 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 6 AMPULHydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus … [L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect.
Products: Atarax Im Sol 50mg/ml, AA PHARMA HYDROXYZINE CAPSULE 10 mg