Search
Lansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigational[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) … Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole.
Mixtures: HELIPAK 500 + 30 + 1000mg TEDAVİ PAKETİ, 7 TABLETCategories: P-glycoprotein inhibitors, P-glycoprotein substratesOxybenzone
go.drugbank.com/drugs/DB01428ApprovedIt is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays. … Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents.
Mixtures: Sea Results Line Resolution Sea Results Line Resolution SPF30, Linea Jose Ignacio Sunscreen Broad Spectrum SPF30Categories: Compounds used in a research, industrial, or household settingOligodendrocyte transcription factor 2
go.drugbank.com/bio_entities/BE0014194TargetHumansRequired for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. … Works in coordination with ZNF488 to promote oligodendrocyte differentiation. Orchestrates progenitor cell fates during cortical gliogenesis and gliomagenesis.
Synonyms: Class E basic helix-loop-helix protein 19Water
go.drugbank.com/drugs/DB09145ApprovedInvestigationalWater is a liquid at standard ambient temperature and pressure, but it often co-exists on Earth with its solid state, ice; and gaseous state, steam (water vapor). … Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms.
Mixtures: IC-Green, IC-GreenProducts: N/A, TACEX-IMQuinapril
go.drugbank.com/drugs/DB00881ApprovedInvestigational[L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … [A184844] Quinapril was granted FDA approval on 19 November 1991.[L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.[L8423]
Mixtures: QUINAPRIL E IDROCLOROTIAZIDE ACTAVIS, QUINAPRIL E IDROCLOROTIAZIDE MYLAN GENERICSCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin SystemOsimertinib
go.drugbank.com/drugs/DB09330ApprovedInvestigationalIn contrast, third-generation inhibitors are specific for the gate-keeper T790M mutations which increases ATP binding activity to EGFR and result in poor prognosis for late-stage disease. … [A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamideBelumosudil
go.drugbank.com/drugs/DB16703ApprovedInvestigational[A236644,L34759] Belumosudil was first approved by the FDA in July 2021, under the brand name Rezurock, for the treatment of chronic GVHD in patients who have tried and failed at least two prior lines … [L34749] In the treatment of GVHD, a condition in which donor T-cells begin to attack recipient tissues following allogeneic hematopoeitic stem cell transplantation (HSCT), belumosudil helps to resolve
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesTazobactam
go.drugbank.com/drugs/DB01606ApprovedInvestigationalIt is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections. … and mortality in hospitalized patients.
Mixtures: Zosyn in Galaxy Containers, Zosyn in Galaxy ContainersCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingBelinostat
go.drugbank.com/drugs/DB05015ApprovedInvestigationalThe safety and efficacy of belinostat is currently being evaluated for use in combination with traditional front-line therapies for the treatment of PTCL. … It was US-approved in July 2014 as a therapeutic agent for relapsed or refractory peripheral T-cell lymphoma.
Synonyms: (2E)-N-HYDROXY-3-(3-(PHENYLSULFAMOYL)PHENYL)PROP-2-ENAMIDE, N-Hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamideCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexManganese gluconate
go.drugbank.com/drugs/DB11141ApprovedManganese gluconate is a direct ingredient in food substances as a nutrient supplement. In pharmaceutical preparations it is used as a [DB06757] supplement. … It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to form a slightly pink powder.
Synonyms: Manganese(II) gluconate, Manganese D-gluconateMixtures: Vitamin E 400 Iu With Selenium, Vitamin C & Manganese, E 400iu W Selenium 100mcg