Search

Displaying results 1321 - 1330 of 10000 in total
  1. Drug

    Tobramycin

    go.drugbank.com/drugs/DB00684
    ApprovedInvestigational

    [L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics … [A232294, A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a variety of forms for administration by inhalation, injection, and external application to

    Mixtures: TOBRAMISOL D®, GOTABIOTIC(R)F OFTALMICOCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  2. Drug

    Clobenzorex

    go.drugbank.com/drugs/DB13561
    Investigational

    Products: ITRAVIL AP, OBECLOX LP
  3. Drug

    Gentamicin

    go.drugbank.com/drugs/DB00798
    ApprovedInvestigationalVet approved

    Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity

    International brands: Spectro-Genta, G-MycinMixtures: Amolg A, SAEROGENTA-A CREAM
  4. Drug

    Sugammadex

    go.drugbank.com/drugs/DB06206
    ApprovedInvestigational

    Sugammadex provides a new treatment option to reverse the effects of those medications and possibly help patients recover sooner post-surgery. … Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery.

    Categories: Compounds used in a research, industrial, or household settingProducts: SUGAMMADEX SUN, Sugammadex Aguettant 10 mg/ml Injektionslösung in einer Fertigspritze
  5. Drug

    Amlodipine

    go.drugbank.com/drugs/DB00381
    ApprovedInvestigational

    Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_. … Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than

    Synonyms: (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylateInternational brands: Atecard-AM, Amlodipine 5
  6. Drug

    Oxygen

    go.drugbank.com/drugs/DB09140
    ApprovedInvestigationalVet approved

    Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in … Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy.

    Mixtures: Oxygen In Helium Mix, Nitrous Oxide In OxygenProducts: N/A, OXIGENO MEDICINAL 93% V/V
  7. Drug

    Ramipril

    go.drugbank.com/drugs/DB00178
    ApprovedInvestigational

    Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).

    Mixtures: RAMIPLUS AL 5MG/25MG, RAMIPLUS AL 5MG/25MGCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Rosuvastatin

    go.drugbank.com/drugs/DB01098
    ApprovedInvestigational

    of death in high-income countries and a major cause of morbidity around the world. … [A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular

    Synonyms: (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid, (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acidMixtures: ROSUVINA LEGRAND® E 10/40, ROSUVINA LEGRAND® E 10/20
  9. Drug

    Acetaminophen

    go.drugbank.com/drugs/DB00316
    ApprovedInvestigational

    FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent tablets, injection, suppository, and other forms. … pregnancy remains a first-line therapeutic option when used at the lowest effective dose for the shortest required duration.

    Synonyms: N-acetyl-p-aminophenol, 4-acetamidophenolInternational brands: Dapa X-S, Anacin-3
  10. Indication

    Fabry's Disease

    go.drugbank.com/conditions/DBCOND0028300
    Drugs: Agalsidase alfa · Agalsidase beta · Migalastat · Pegunigalsidase alfa
    Synonyms: Alpha-galactosidase A deficiency, Alpha galactosidase A deficiency