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Displaying results 1331 - 1340 of 3733 in total
  1. Drug

    Labetalol

    go.drugbank.com/drugs/DB00598
    ApprovedInvestigational

    Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension. Labetalol was granted FDA approval on 1 A...

    Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor Antagonists
  2. Drug

    Triclocarban

    go.drugbank.com/drugs/DB11155
    Approved

    In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products containing triclocarban due to negative health effects such as bacterial resistance or hormonal

  3. Drug

    Aluminum chlorohydrate

    go.drugbank.com/drugs/DB11573
    Approved

    It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.

    Products: Jean Nate Roll-ON Antiperspirant
  4. Drug

    Magnesium salicylate

    go.drugbank.com/drugs/DB01397
    Approved

    It is available in several over-the-counter (OTC) formulations.

  5. Drug

    Pitolisant

    go.drugbank.com/drugs/DB11642
    ApprovedInvestigational

    Pitolisant is a selective antagonist or inverse agonist of the histamine H3 receptor used to treat type 1 or 2 narcolepsy.

    Categories: Histamine-3 Receptor Antagonist/Inverse Agonist, Histamine-3 (H3) Receptor Antagonists/Inverse Agonists
  6. Drug

    Tannic acid

    go.drugbank.com/drugs/DB09372
    ApprovedInvestigational

    Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid. Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercu...

    Mixtures: Germa Tan
  7. Drug

    Viltolarsen

    go.drugbank.com/drugs/DB15005
    ApprovedInvestigational

    Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A relat...

  8. Drug

    Lanolin

    go.drugbank.com/drugs/DB11112
    Approved

    Lanolin is used as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and facial cosmetics. … The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments [L2583].

  9. Drug

    Interferon alfacon-1

    go.drugbank.com/drugs/DB00069
    ApprovedWithdrawn

    Interferon alfacon-1 differs from interferon alfa-2b at 20/166 amino acids (88% homology), and comparison with interferon-beta shows identity at over 30% of the amino acid positions. … Prior to final purification, Interferon alfacon-1 is allowed to oxidize to its native state, and its final purity is achieved by sequential passage over a series of chromatography columns.

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  10. Drug

    Guanidine

    go.drugbank.com/drugs/DB00536
    Approved

    A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism.