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Ensulizole
go.drugbank.com/drugs/DB11115ApprovedEnsulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. … It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths.
Mixtures: Creme Solaire Haute Protection Special Enfants Et Peaux Reactives Au Soleil SPF 30, Cellular Aw Sun Block SPF 50Chlordiazepoxide
go.drugbank.com/drugs/DB00475ApprovedIllicitAn anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Mixtures: AA PHARMA CHLORAX CAPSULE, Nu-chlorax Capsules USPCorifollitropin alfa
go.drugbank.com/drugs/DB09066ApprovedInvestigationalIn July 2014, Merck announced the receipt of a Complete Response Letter (CRL) from the U.S. FDA for its New Drug Application for this drug. … Multiple studies and a meta-analysis suggest that corifollitropin alfa is as efficacious as recombinant FSH in terms of live birth rate, ongoing pregnancy rate, as well as clinical pregnancy rate.
Phenmetrazine
go.drugbank.com/drugs/DB00830ApprovedIllicitA sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine.
Quinacrine
go.drugbank.com/drugs/DB01103InvestigationalAn acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. … It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Daratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigational[A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. … [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and light chain (AL) amyloidosis in combination with other drugs.
Nuclear receptor subfamily 0 group B member 1
go.drugbank.com/bio_entities/BE0000074TargetHumansNuclear receptor that lacks a DNA-binding domain and acts as a corepressor that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions (PubMed:12482977, PubMed
Polypeptides: Nuclear receptor subfamily 0 group B member 1Synonyms: Nuclear receptor DAX-1Nuclear receptor subfamily 1 group D member 1
go.drugbank.com/bio_entities/BE0009347TargetHumansActs as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. … Binds as a monomer to a response element composed of the consensus half-site motif 5'-[A/G]GGTCA-3' preceded by an A/T-rich 5' sequence (RevRE), or as a homodimer to a direct repeat of the core motif spaced
Polypeptides: Nuclear receptor subfamily 1 group D member 1Leucine-rich repeat serine/threonine-protein kinase 2
go.drugbank.com/bio_entities/BE0009457TargetHumansTogether with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose-6-phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent
Polypeptides: Leucine-rich repeat serine/threonine-protein kinase 2Tyrosine-protein phosphatase non-receptor type substrate 1
go.drugbank.com/bio_entities/BE0010650TargetHumansReceptor for THBS1 (PubMed:24511121). Interaction with THBS1 stimulates phosphorylation of SIRPA (By similarity). … Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin.
Polypeptides: Tyrosine-protein phosphatase non-receptor type substrate 1Synonyms: Inhibitory receptor SHPS-1, Macrophage fusion receptor