Search

Displaying results 1361 - 1370 of 10000 in total
  1. Drug

    Isatuximab

    go.drugbank.com/drugs/DB14811
    ApprovedInvestigational

    Isatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line. … [L12099] It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma.

    Products: SARCLİSA 100 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, SARCLİSA 500 MG/25 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET
  2. Drug

    Lornoxicam

    go.drugbank.com/drugs/DB06725
    ApprovedInvestigational

    Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. … Lornoxicam is approved for use in Japan.

    Mixtures: LORNOPAR 8/300 MG EFERVESAN TABLET ,20 ADETCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 Substrates
  3. Drug

    Potassium acetate

    go.drugbank.com/drugs/DB14498
    Approved

    Mixtures: NUTRIPLUS LIPID SENZA ELETTROLITI, NUTRIPLUS LIPID SENZA ELETTROLITIProducts: Potassium Acetate Inj 2meq/ml, Potassium Acetate Inj 392mg/ml USP
  4. Drug

    Acriflavine

    go.drugbank.com/drugs/DB13373
    Investigational

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 3-RingProducts: DERMOPLEX BURN AID CREAM, FLAVISEPT CREAM 0.1%W/W
  5. Drug

    Bretylium

    go.drugbank.com/drugs/DB01158
    Approved

    Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular … The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels.

    Synonyms: 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium, N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminiumMixtures: Bretylium Tosylate 0.4% and Dextrose 5% Inj, Bretylium Tosylate 0.2% and Dextrose 5% Inj
  6. Target

    Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

    go.drugbank.com/bio_entities/BE0004551
    TargetHumans

    Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells … Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.

    Polypeptides: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
  7. Indication

    Hepatitis C Infections

    go.drugbank.com/conditions/DBCOND0072126
    Drugs: Interferon alfa
    Synonyms: Hep non-A non-B, Hepatitis non-A non-B
  8. Drug

    Sodium acetate

    go.drugbank.com/drugs/DB09395
    ApprovedInvestigational

    Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. … Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions.

    Mixtures: NUTRIPLUS LIPID SENZA ELETTROLITI, NUTRIPLUS LIPID SENZA ELETTROLITISynonyms: Acetic acid, sodium salt (1:1)
  9. Drug

    Rasagiline

    go.drugbank.com/drugs/DB01367
    ApprovedInvestigational

    Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.

    Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesSynonyms: (R)-N-2-Propynyl-1-indanamine, (1R)-N-propargylindan-1-amine
  10. Indication

    Recurrent Miscarriages

    go.drugbank.com/conditions/DBCOND0032265
    Drugs: Dydrogesterone
    Synonyms: Investigation or care in a nonpregnant woman with history of recurrent pregnancy loss