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OTL-203
go.drugbank.com/drugs/DB18643InvestigationalOTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Synonyms: Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase geneObinutuzumab
go.drugbank.com/drugs/DB08935ApprovedInvestigational[L54521] Like other drugs in its class, obinutuzumab targets the CD20 antigen expressed on the surface of pre-B and mature B lymphocytes, mediating B-cell lysis. … This chemical modification significantly enhances its affinity for FcγRIII receptors on immune effector cells.
Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: GAZYVA 1000 MG/ 40 ML CONCENTRATE FOR SOLUTION FOR INFUSION, GAZYVA ® CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN 1000 MG / VIAL 40 MLAmitriptyline
go.drugbank.com/drugs/DB00321ApprovedInvestigationalELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. … [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.[A174661]
Synonyms: 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamineProducts: AMITRIPTILINA EG, AMITRIPTYLIN-NEURAX 100 MGIdarucizumab
go.drugbank.com/drugs/DB09264ApprovedApproved under the tradename Praxbind (FDA), idarucizumab is indicated for the emergency treatment of dabigatran-associated bleeding in life-threatening or surgically induced situations. … Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its
Products: PRAXBIND Solution for Injection/Infusion 50 mg/ml, PRAXBIND SOLUTION FOR INJECTION/INFUSION 50 MG/MLCarboxymethylcellulose
go.drugbank.com/drugs/DB11059ApprovedInvestigationalIt is added in food products as a viscosity modifier or thickener and emulsifier. … It is also one of the most common viscous polymers used in artificial tears, and has shown to be effective in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining [A33029
Categories: Compounds used in a research, industrial, or household settingProducts: EyS-ED, LAGRIMART ® 5 MG/ MLAtracurium
go.drugbank.com/drugs/DB13295ApprovedInvestigationalWithdrawnProducts: TRACRİUM 25 MG/2.5 ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 5 ADET, TRACRİUM 50 MG/5 ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 5 ADETMirikizumab
go.drugbank.com/drugs/DB14910ApprovedInvestigational[L46252] It was officially approved in the EU in May 2023[L48656] and Canada in July 2023[L48661], and was eventually approved in the US in October 2023[L48651] for the treatment of adult patients with … [L46237,L46257] Mirikizumab is approved in Japan[L46252] and received a positive opinion from the EMA's Committee for Medicinal Products for Human Use in March 2023.
Products: Misuvya 100 mg/1 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 2 ADET, Misuvya 300 mg/15 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 ADETCloperastine
go.drugbank.com/drugs/DB09002InvestigationalCloperastine is a cough suppressant that acts on the central nervous system.
Products: FENTUS 708 MG/100 ML ORAL SÜSPANSİYON, 200 ML, FENTUS 708 MG/100 ML ORAL SÜSPANSİYON, 100 MLPancuronium
go.drugbank.com/drugs/DB01337ApprovedAs a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release.
Products: BROMURO DE PANCURONIO 4 MG/2 ML, BROMURO DE PANCURONIO 2 MG/MLAMP-201
go.drugbank.com/drugs/DB18663ExperimentalAMP-201 comprises an adeno-associated virus type 8 vector (AAV8) encoding the collagen Q gene (COLQ). It is under investigation for the treatment of collagen Q congenital myasthenia.