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Antihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalPEGylation is the covalent attachment of a polyethylene glycol polymer, called PEG, to a drug or protein. … PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation in the plasma [L1529].
Categories: Compounds used in a research, industrial, or household settingProducts: ADYNOVATE 500®IU / VIAL, ADYNOVATE®250IU/VIALIsatuximab
go.drugbank.com/drugs/DB14811ApprovedInvestigationalIsatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line. … [L12099] It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma.
Products: SARCLİSA 100 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, SARCLİSA 500 MG/25 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETLornoxicam
go.drugbank.com/drugs/DB06725ApprovedInvestigationalLornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. … Lornoxicam is approved for use in Japan.
Mixtures: LORNOPAR 8/300 MG EFERVESAN TABLET ,20 ADETCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesOfloxacin
go.drugbank.com/drugs/DB01165ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Categories: Topoisomerase II Inhibitors, 4-QuinolonesSynonyms: 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acidAcriflavine
go.drugbank.com/drugs/DB13373InvestigationalCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 3-RingProducts: DERMOPLEX BURN AID CREAM, FLAVISEPT CREAM 0.1%W/WBretylium
go.drugbank.com/drugs/DB01158ApprovedBretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular … The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels.
Mixtures: Bretylium Tosylate 0.4% and Dextrose 5% Inj, Bretylium Tosylate 0.2% and Dextrose 5% InjSynonyms: 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium, N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminiumCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
go.drugbank.com/bio_entities/BE0004551TargetHumansRecruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells … Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.
Polypeptides: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1Hepatitis C Infections
go.drugbank.com/conditions/DBCOND0072126Drugs: Interferon alfaSynonyms: Hep non-A non-B, Hepatitis non-A non-BRecurrent Miscarriages
go.drugbank.com/conditions/DBCOND0032265Drugs: DydrogesteroneSynonyms: Investigation or care in a nonpregnant woman with history of recurrent pregnancy lossGadoversetamide
go.drugbank.com/drugs/DB00538ApprovedGadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Categories: Compounds used in a research, industrial, or household settingProducts: OPTIMARK 500 MIKROMOL/ML IV. ENJ. ICIN COZ. ICEREN FLAKON, 10 ML, OPTIMARK 500 MIKROMOL/ML IV. ENJ. ICIN COZ. ICEREN FLAKON, 15 ML