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Chlorambucil
go.drugbank.com/drugs/DB00291ApprovedInvestigationalA nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in t...
Synonyms: 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid, γ-[p-di(2-chloroethyl)aminophenyl]butyric acidProducts: LEUKERAN 2 MG TABLET, 25 ADET, Leukeran 2 mg - FilmtablettenDiazoxide
go.drugbank.com/drugs/DB01119ApprovedInvestigationalDiazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels. It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic...
Synonyms: 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxideCategories: Heterocyclic Compounds, 2-RingZalcitabine
go.drugbank.com/drugs/DB00943ApprovedWithdrawnA dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA cha...
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one, 2',3'-DideoxycytidineMelperone
go.drugbank.com/drugs/DB09224InvestigationalMelperone has been used for a span of greater than 30 years in the European Union [L1316].
Products: MELPERON-NEURAX 10 MG, MELPERON-NEURAX 50 MGRemdesivir
go.drugbank.com/drugs/DB14761ApprovedInvestigationalSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which is a respiratory disease that is capable of progressing to viral pneumonia … [L12174, L12177] After initially being granted an FDA Emergency Use Authorization (EUA) on May 1st, 2020,[L13236] remdesivir was fully approved by the FDA for the treatment of COVID-19 on October 22
Categories: MATE 1 Inhibitors, Approved Treatments for COVID-19Products: VEKLURY 100 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADETMizolastine
go.drugbank.com/drugs/DB12523ApprovedMizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).
Categories: Heterocyclic Compounds, 2-RingProducts: MIZOLEN 10 MG TABLETAS DE LIBERACION PROLONGADATrihexyphenidyl
go.drugbank.com/drugs/DB00376ApprovedInvestigational[L31843] Trihexyphenidyl was granted FDA approval on 13 May 1949.[L31768]
Categories: Heterocyclic Compounds, 1-RingProducts: BENZHEXOL TABLETS 2 MG, BEAHEXOL TABLETS 2 mgCefepime
go.drugbank.com/drugs/DB01413ApprovedInvestigationalCefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics. Cefepime is ...
Categories: Heterocyclic Compounds, 2-RingSynonyms: (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylateUrapidil
go.drugbank.com/drugs/DB12661InvestigationalUrapidil has been investigated for the treatment of Hypertension During Pre-Eclampsia.
Categories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 1-RingProducts: UPADİL 50 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, EBRASEL 50 MG/10 ML I.V. ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 5 ADETGroup 10 secretory phospholipase A2
go.drugbank.com/bio_entities/BE0000070TargetEnzymeHumansSecretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids (PubMed:12021277, PubMed:9188469). Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preferen...
Polypeptides: Group 10 secretory phospholipase A2Synonyms: Phosphatidylcholine 2-acylhydrolase 10