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Displaying results 1371 - 1380 of 10000 in total
  1. Drug

    Cangrelor

    go.drugbank.com/drugs/DB06441
    ApprovedInvestigational

    Cangrelor was approved by the FDA in June 2015 for intravenous application. … An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset

    Synonyms: [dichloro-[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acidCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Mefloquine

    go.drugbank.com/drugs/DB00358
    Approved

    The 2020 World Health Organization malaria report indicates a 60% decrease in the global malaria fatality rate between 2000 to 2019. … [L30618] Despite this, malaria remains a significant cause of morbidity and mortality; 90% of deaths from malaria occur in Africa.

    Synonyms: .-2-PIPERIDYL-2,8-BIS(TRIFLUOROMETHYL)-4-QUINOLINEMETHANOL, .-2-PIPERIDINYL-2,8-BIS(TRIFLUOROMETHYL)-, (R*,S*)-(±)-Mixtures: อาร์ทีซูเนทและเมฟลอควินไฮโดรคลอไรด์ 100/220 มก., อาร์ทีซูเนทและเมฟลอควินไฮโดรคลอไรด์ 25/55 มก.
  3. Drug

    Dantrolene

    go.drugbank.com/drugs/DB01219
    ApprovedInvestigational

    Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-((5-(p-nitrophenyl)furfurylidene)amino)hydantoin
  4. Drug

    Temazepam

    go.drugbank.com/drugs/DB00231
    Approved

    In particular, before temazepam saw regular prescription use in civilians it was - and still is - employed by the US military as a sedative-hypnotic medication to be taken by soldiers, pilots, etc. to … synthesis of temazepam was established by 1965 [A175333], mainstream contemporary use of the medication did not occur until it's legitimate use as treatment for insomnia was accepted and approved later on

    Products: TEMAZEP - CT 10 MG KAPSELN, Temazepam-30
  5. Drug

    Mecobalamin

    go.drugbank.com/drugs/DB03614
    ApprovedInvestigational

    Mixtures: Medi-10, BEGOLIN PLUS 75MG/1MG FILM TABLET, 14 ADETCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Desflurane

    go.drugbank.com/drugs/DB01189
    ApprovedInvestigational

    It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted FDA approval on 18 September 1992.[L30285]

    Synonyms: 1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane, (±)-2-difluoromethyl 1,2,2,2-tetrafluoroethyl etherProducts: DESJOURN % 100 İNHALASYON ÇÖZELTISI , 250 ML, SUPRANE VOLATİL %100 İNHALASYON BUHARI, ÇÖZELTİ, 240 ML
  7. Drug

    Cabotegravir

    go.drugbank.com/drugs/DB11751
    ApprovedInvestigational

    [A227668,L31193] Cabotegravir was granted FDA approval on 21 January 2021 in combination with rilpivirine to treat HIV-1 infection in virologically suppressed individuals. … Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, [rilpivirine].

    Categories: Heterocyclic Compounds, 1-Ring, Organic Anion Transporter 1 InhibitorsProducts: Vocabria 30 mg Film Kaplı Tablet, 30 ADET, Vocabria 400 mg/2 ml Enjeksiyonluk Uzatılmış Salımlı Süspansiyon, 1 ADET
  8. Drug

    Cloxacillin

    go.drugbank.com/drugs/DB01147
    ApprovedInvestigationalVet approved

    A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.

    Synonyms: (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Tafluprost

    go.drugbank.com/drugs/DB08819
    Approved

    Tafluprost was approved for use in the U.S. on February 10, 2012. … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

    Mixtures: TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container, Taptiqom 15 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisProducts: SAFLUTAN 15 MCG/ML TEK DOZLUK GOZ DAMLASI, 30 ADET, Saflutan 15 Mikrogramm/ml Augentropfen, Lösung
  10. Drug

    Amiloride

    go.drugbank.com/drugs/DB00594
    ApprovedInvestigational

    Amiloride is used in conjunction with diuretics to spare potassium loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705) … This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct.

    Mixtures: Riva-amilzide 5/50 mg, Nu-amilzide 5/50 Mg TabCategories: Heterocyclic Compounds, 1-Ring