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Nogalonic acid methyl ester cyclase
go.drugbank.com/bio_entities/BE0003204TargetStreptomyces nogalaterCatalyzes the formation of nogalaviketone from nogalonic acid methyl ester (NAME), the last ring-closure step in the biosynthesis of nogalamycin.
Polypeptides: Nogalonic acid methyl ester cyclaseFree fatty acid receptor 4
go.drugbank.com/bio_entities/BE0003399TargetHumansConsequently stimulates fatty acid uptake and oxidation in mitochondria together with UCP1-mediated thermogenic respiration, eventually reducing fat mass (By similarity). … G protein-coupled receptor for long-chain fatty acids (LCFAs) with a major role in adipogenesis, energy metabolism and inflammation.
Polypeptides: Free fatty acid receptor 4Synonyms: Omega-3 fatty acid receptor 1Fatty acid-binding protein, intestinal
go.drugbank.com/bio_entities/BE0003591CarrierTargetHumansFABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. … Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids.
Polypeptides: Fatty acid-binding protein, intestinalSynonyms: Fatty acid-binding protein 2, Intestinal-type fatty acid-binding proteinIleal sodium/bile acid cotransporter
go.drugbank.com/bio_entities/BE0003643TransporterTargetHumansTransports various bile acids, unconjugated or conjugated, such as cholate and taurocholate (PubMed:7592981, PubMed:9458785, PubMed:9856990). … Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling
Polypeptides: Ileal sodium/bile acid cotransporterSynonyms: Ileal Na(+)/bile acid cotransporter, Apical sodium-dependent bile acid transporterAlpha-1-acid glycoprotein 2
go.drugbank.com/bio_entities/BE0003663TargetHumansAlso binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction
Polypeptides: Alpha-1-acid glycoprotein 2Folic acid synthesis protein FOL1
go.drugbank.com/bio_entities/BE0004658TargetBaker's yeastCatalyzes three sequential steps of tetrahydrofolate biosynthesis.
Polypeptides: Folic acid synthesis protein FOL1Free fatty acid receptor 2
go.drugbank.com/bio_entities/BE0010131TargetHumansIn omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. … Among SCFAs, the fatty acids containing less than 6 carbons, the most potent activators are probably acetate, propionate and butyrate (PubMed:12496283, PubMed:12711604).
Polypeptides: Free fatty acid receptor 2Cellular retinoic acid-binding protein 1
go.drugbank.com/bio_entities/BE0000508CarrierTransporterTargetHumansCytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors
Polypeptides: Cellular retinoic acid-binding protein 1Synonyms: Cellular retinoic acid-binding protein IProton-coupled amino acid transporter 1
go.drugbank.com/bio_entities/BE0000536TargetTransporterHumansElectrogenic proton/amino acid symporter with selectivity for small apolar L-amino acids, their D-enantiomers and selected amino acid derivatives such as 4-aminobutanoate/GABA (PubMed:12527723, PubMed: … May be involved in the efflux from the lysosomal compartment of neutral amino acids resulting from proteolysis (By similarity).
Polypeptides: Proton-coupled amino acid transporter 1Synonyms: Proton/amino acid transporter 1Retinoic acid receptor responder protein 1
go.drugbank.com/bio_entities/BE0000653TargetHumansInhibitor of the cytoplasmic carboxypeptidase AGBL2, may regulate the alpha-tubulin tyrosination cycle
Polypeptides: Retinoic acid receptor responder protein 1