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Etoposide Action Pathway
smpdb.ca/view/SMP0000442Drug actionEtoposide is a medication commonly sold as Vepesid, or Etopophos. It is a type of chemotherapy. It is used to treat many types of cancers, including nonlymphocytic leukemia and testicular cancer. Etoposide is semisynthetic and a derivati...
Teniposide Metabolism Pathway
smpdb.ca/view/SMP0000602Drug metabolismTeniposide is a type of chemotherapy drug, derived from the epipodophyllotoxin form the American Mayapple plant. Teniposide is related to etoposide, another anti-cancer drug.
Lidocaine (Local Anaesthetic) Metabolism Pathway
smpdb.ca/view/SMP0000620Drug metabolismLidocaine diffuses across the neuronal plasma membrane in its uncharged base form. … Once inside the cytoplasm, it is protonated and this protonated form enters and blocks the pore of the voltage-gated sodium channel from the cytoplasmic side.
Codeine Metabolism Pathway
smpdb.ca/view/SMP0000621Drug metabolismOpiate receptors are coupled with G-protein receptors and function as both positive and negative regulators of synaptic transmission via G-proteins that activate effector proteins. Binding of the opiate stimulates the exchange of GTP for...