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Ritlecitinib
go.drugbank.com/drugs/DB14924ApprovedInvestigationalRitlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family. In June 2023, it was approved by the FDA for the treatment of severe a...
Synonyms: 2-propen-1-one, 1-((2S,5R)-2-methyl-5-(7H-pyrrolo(2,3-D)pyrimidin-4-ylamino)-1-piperidinyl)-Lormetazepam
go.drugbank.com/drugs/DB13872ApprovedLormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Synonyms: 7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-oneChlorzoxazone
go.drugbank.com/drugs/DB00356ApprovedA centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Ph...
Synonyms: 5-chlorobenzoxazolin-2-one, 5-chloro-3H-benzooxazol-2-oneHydrocodone
go.drugbank.com/drugs/DB00956ApprovedIllicitInvestigationalHydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely b...
Synonyms: 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-oneAzacitidine
go.drugbank.com/drugs/DB00928ApprovedInvestigationalThe other one is through the inhibition of DNA methyltransferase, impairing DNA methylation. … One of them is the induction of cytotoxicity. As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and inhibiting protein and DNA synthesis.
Synonyms: 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-oneDiazepam
go.drugbank.com/drugs/DB00829ApprovedIllicitInvestigationalVet approvedA benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment o...
Synonyms: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-oneNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approvedNaloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxon...
Synonyms: 17-allyl-3,14-dihydroxy-4,5α-epoxymorphinan-6-oneMixtures: TILIDIN AL COMP, TILIDIN AL COMPPseudoephedrine
go.drugbank.com/drugs/DB00852ApprovedPseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system. Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first ...
Mixtures: Facol Classic One, Cold & Flu-IN-oneProducts: Care One Suphedrine Nasal Decongestant Non DrowsyTrolamine salicylate
go.drugbank.com/drugs/DB11079ApprovedTrolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain ass...
Products: Care One Analgesic, Tommie Copper Pain ReliefLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid ...
Products: Care One Anti Diarrheal, Care One anti diarrheal loperamide hydrochloride