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Afizagabar
go.drugbank.com/drugs/DB21439InvestigationalAfizagabar is a small molecule drug. Afizagabar is under investigation in clinical trial NCT02877615 (Efficacy and Safety Trial With S 44819 After Recent Ischemic Cerebral Event). … Afizagabar has a monoisotopic molecular weight of 365.06 Da.
Categories: GABA-A Receptor AntagonistsOctisalate
go.drugbank.com/drugs/DB11062ApprovedOctyl salicylate appears to have a good safety profile. It covers wavelength in the range 295-315 nm, peak at 307-310 nm. It is an ester of salicylic acid and 2-ethylhexanol. … Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA.
Mixtures: Creme De Jour Au Retinol, Erborian BB creme au Ginseng chocolate SPF 20Categories: Compounds used in a research, industrial, or household settingCelivarone
go.drugbank.com/drugs/DB16012InvestigationalCalibrator for the Maintenance of Sinus Rhythm in Patients With Recent Atrial Fibrillation/flutter). … Celivarone is under investigation in clinical trial NCT00233441 (Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 Mg OD With Amiodarone as
Octocrylene
go.drugbank.com/drugs/DB09535ApprovedOctocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. … What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin damage from prolonged sun exposure.
Mixtures: Creme Pour Peaux Intolerantes Au Soleil, Spray Pour Peaux Intolerantes Au SoleilTransient receptor potential cation channel subfamily V member 1
go.drugbank.com/bio_entities/BE0001023TargetHumansActs as ionotropic endocannabinoid receptor with central neuromodulatory effects. … Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL.
Polypeptides: Transient receptor potential cation channel subfamily V member 1Synonyms: Capsaicin receptor, Vanilloid receptor 1Low affinity immunoglobulin gamma Fc region receptor II-a
go.drugbank.com/bio_entities/BE0002098TargetHumansLow affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens
Polypeptides: Low affinity immunoglobulin gamma Fc region receptor II-aSynonyms: IgG Fc receptor II-aTransient receptor potential cation channel subfamily V member 2
go.drugbank.com/bio_entities/BE0009158TargetHumansCalcium-permeable, non-selective cation channel (PubMed:10201375). Seems to be regulated, at least in part, by growth factors, such as IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells...
Polypeptides: Transient receptor potential cation channel subfamily V member 2Synonyms: Vanilloid receptor-like protein 1Ankyrin repeat and protein kinase domain-containing protein 1
go.drugbank.com/bio_entities/BE0009411TargetHumansPolypeptides: Ankyrin repeat and protein kinase domain-containing protein 1Transient receptor potential cation channel subfamily M member 3
go.drugbank.com/bio_entities/BE0009808TransporterHumansSuggested to function as an ionotropic steroid receptor in beta-cell, indeed pregnenolone sulfate leads to Ca(2+) influx and enhanced insulin secretion.
Polypeptides: Transient receptor potential cation channel subfamily M member 3Synonyms: Long transient receptor potential channel 3Vepdegestrant
go.drugbank.com/drugs/DB19006ApprovedInvestigationalVepdegestrant is a potent, selective, and orally bioavailable PROteolysis TArgeting Chimera (PROTAC) small molecule estrogen receptor (ER) degrader. … [A275507, A275508, A275511] It was identified through a targeted medicinal chemistry optimization campaign to act as a next-generation endocrine therapy for breast cancer.
Categories: Selective Estrogen Receptor Degraders