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Displaying results 1401 - 1410 of 5504 in total
  1. Drug

    Lisdexamfetamine

    go.drugbank.com/drugs/DB01255
    ApprovedInvestigational

    [A2230] It was also approved by Health Canada in February 2009.

    Products: SAMEXID® 50MG
  2. Drug

    Momelotinib

    go.drugbank.com/drugs/DB11763
    ApprovedInvestigational

    MF includes primary MF (PMF), post-polycythemia vera (PV) MF, and post-essential thrombocythemia (ET) MF. Clinical manifestations of MF include anemia and thrombocytosis. … It is a competitive inhibitor of JAK ATP binding.[A261566] First approved by the FDA on September 15, 2023,[L48206] momelotinib is used to treat myelofibrosis.

  3. Drug

    Methionine

    go.drugbank.com/drugs/DB00134
    ApprovedInvestigationalNutraceutical

    It is a chelating agent for heavy metals.

    Mixtures: Clinimix E, Clinimix ESynonyms: Met
  4. Drug

    Sodium glycerophosphate

    go.drugbank.com/drugs/DB09561
    Approved

    It is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667].

    Mixtures: Olimel 7.6% E, Olimel 4.4% E
  5. Drug

    Tyrosine

    go.drugbank.com/drugs/DB00135
    ApprovedInvestigationalNutraceutical

    In animals it is synthesized from [phenylalanine]. It is also the precursor of [epinephrine], thyroid hormones, and melanin.

    Mixtures: Clinimix E, Clinimix E
  6. Drug

    Tegaserod

    go.drugbank.com/drugs/DB01079
    ApprovedWithdrawn

    [L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause dangerous cardiovascular … in its history of regulatory approval, ever since its first introduction in 2002 tegaserod remains the only therapy for IBS-C that possesses the unique mechanism of action of acting on serotonin-4 (5-HT

  7. Drug

    Amifampridine

    go.drugbank.com/drugs/DB11640
    Approved

    Slow acetylators were at higher risk for experiencing drug-associated adverse reactions, such as paresthesias, nausea, and headache [F272]. … It is currently used as the first-line symptomatic treatment for LEMS in adult patients and is ideally given as oral tablets in divided doses, three or four times a day.

  8. Drug

    Padimate O

    go.drugbank.com/drugs/DB11570
    Approved

    It is a structurally-related compound to [DB02362] that absorbs UV-B rays to prevent photodamage. … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic effects on yeast i_n vivo_ [A32458].

    Mixtures: Ea Eight Hr Lip Sheer Tints, Banana Boat Vitamin E Lip Balm Spf30Products: Mentholatum Natural Ice Lipbalm With Moisturizing Vitamin E & Aloe Vera
  9. Drug

    Lucinactant

    go.drugbank.com/drugs/DB04897
    Approved

    It is completely devoid of animal-derived components. FDA approved on March 6, 2012. … More specifically, it mimics the C-terminal amphipathic helical domain of this protein.

  10. Drug

    Alginic acid

    go.drugbank.com/drugs/DB13518
    ApprovedInvestigationalWithdrawn

    It is present in cell walls of brown algae where it forms a viscous gel when binding with water. … It is also available in oral dietary supplements and is found in antacids such as Gaviscon to inhibit gastroesophageal reflux by creating a physical barrier in presence of gastric acid [F46].

    Mixtures: MILACID® SACHET POR 10ML SABOR MENTA, GAVISCON BRUCIORE E INDIGESTIONE