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Isoleucine
go.drugbank.com/drugs/DB00167ApprovedInvestigationalNutraceuticalIt is an isomer of leucine. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
Mixtures: ASCE plus Derma Signal Kit SRLV S, ASCE plus Derma Signal Kit SRLV SSynonyms: (2S,3S)-2-Amino-3-methylpentanoic acid, 2-Amino-3-methylvaleric acidValbenazine
go.drugbank.com/drugs/DB11915ApprovedInvestigationalThis approval was supported by positive results in multiple trials, including the KINECT-HD Phase 3 study and the ongoing KINECT-HD2 open-label extension trial. … [A261165] On April 2017, valbenazine was approved by the FDA under the brand name INGREZZA as the first and only approved treatment for adults with Tardive Dyskinesia (TD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: REMLEAS™ hard capsules 40mgFidanacogene elaparvovec
go.drugbank.com/drugs/DB16783ApprovedInvestigational[L49469] This approval was based on positive results demonstrated in the open-label, single-arm Phase 3 BENEGENE-2 study, where the annualized bleeding rate (ABR) was observed to be 1.3 for the 12 months … [L46691] Hemophilia B is a rare X-linked genetic disorder characterized by abnormal coagulation due to dysfunctional coagulation factor IX with a male incidence estimated to be 1 in 30,000 male births
Prednisolone sodium metazoate
go.drugbank.com/drugs/DB05340InvestigationalATL-2502(Colal-Pred) is an old drug (prednisolone metasulphobenzoate, a steroid) with a new delivery system that releases the medication only in the colon. … Releasing the drug directly into the colon reduces the potential for significant side effects often experienced with steroid drugs. Colal-Pred is being studied for use in ulcerative colitis.
Mixtures: KORTISETIN GÖZ POMADI, 5 G, KORTISETIN GÖZ POMADI, 2.5 GD-glucose
go.drugbank.com/drugs/DB01914ApprovedInvestigationalVet approved[A19399] It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. … [L786] Glucose is listed on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
Synonyms: D-glucose, D(+)-GlucoseSalts: D-glucose monohydratealpha-Tocopherol succinate
go.drugbank.com/drugs/DB14001ApprovedNutraceuticalVet approvedAlpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. … Nevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals.
Mixtures: Ni-C-E-LE Plus, Hyper E TabCategories: Vitamin E, Heterocyclic Compounds, 1-RingElasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigationalThe Moderna COVID-19 Vaccine (mRNA-1273; Elasomeran) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion stabilized spike (S) protein of severe … [L28026] A phase I, open-label, dose-ranging clinical trial (NCT04283461) was initiated in March 2020 in which 45 subjects received two intramuscular doses (on days 1 and 29).
Mixtures: Spikevax Bivalent (original / Omicron Ba.4/5)Synonyms: MRNA-1273 SARS-COV-2Linaclotide
go.drugbank.com/drugs/DB08890ApprovedInvestigational[A260276] It is also a homolog of a heat-stable enterotoxin derived from _Escherichia coli_, the first natural ligand that activates GC-C. … [A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C.
Categories: Guanylate Cyclase-C Agonist, Guanylyl Cyclase C AgonistsSynonyms: -GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL-, CYCLIC (1->6),(2->10),(5->13)-TRIS(DISULFIDE), L-TYROSINE, L-CYSTEINYL-L-CYSTEINYL-L-.ALPHA.Lutropin alfa
go.drugbank.com/drugs/DB00044ApprovedInvestigationalLutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. … Its pharmacological action mimics the biological activity of endogenous LH; an acute rise of LH, or LH surge, in females triggers ovulation and the development of the corpous luteum.
Mixtures: PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET, PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 3 ADETCategories: Sex Hormones and Modulators of the Genital SystemGluconic Acid
go.drugbank.com/drugs/DB13180ApprovedInvestigationalGluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Mixtures: Isolyte S, Isolyte S pH 7.4Synonyms: D-Gluconic Acid