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Displaying results 1421 - 1430 of 10000 in total
  1. Drug

    Enalapril

    go.drugbank.com/drugs/DB00584
    ApprovedInvestigationalVet approved

    Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood … The active metabolite of enalapril competitively inhibits the ACE to hinder the production of angiotensin II, a key component of the renin-angiotensin-aldosterone system that promotes vasoconstriction

    Mixtures: ZANIPRESS 10MG/10MG FTA, ZANIPRESS 20MG/10MG FTACategories: Agents Acting on the Renin-Angiotensin System, P-glycoprotein inhibitors
  2. Drug

    Angiotensin II

    go.drugbank.com/drugs/DB11842
    ApprovedInvestigational

    As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's Giapreza (angiotensin II) Injection for Intravenouse Infusion for the indication of acting as a vasoconstrictor to increase blood pressure … Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy.

    Synonyms: 5-L-isoleucineangiotensin II, 5-isoleucine-angiotensin II
  3. Pathway

    Monoamine Oxidase-A Deficiency (MAO-A)

    smpdb.ca/view/SMP0125595
    Disease

    Momoamine oxidase A (MAO-A) deficiency, or Brunner syndrome, is an X-linked recessive genetic disorder caused by a mutation in the MAOA gene that encodes for monoamine oxidase A. … With the inactivation of MAO-A, 3-methoxytyramine builds up as there are no reactions that use it, and both of these paths lead to a decrease in the concentration of homovanillic acid, as there are no

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Tyrosine · Glutamic acid +20 more
    Enzymes: Amine oxidase [flavin-containing] A
  4. Pathway

    Monoamine Oxidase-A Deficiency (MAO-A)

    smpdb.ca/view/SMP0000533
    Disease

    Momoamine oxidase A (MAO-A) deficiency, or Brunner syndrome, is an X-linked recessive genetic disorder caused by a mutation in the MAOA gene that encodes for monoamine oxidase A. … With the inactivation of MAO-A, 3-methoxytyramine builds up as there are no reactions that use it, and both of these paths lead to a decrease in the concentration of homovanillic acid, as there are no

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Tyrosine · Glutamic acid +20 more
    Enzymes: Amine oxidase [flavin-containing] A
  5. Drug

    FR-234938

    go.drugbank.com/drugs/DB03220
    Experimental

  6. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0001257
    TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

    Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA caus...

    Synonyms: Recombinase A
  7. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0003084
    TargetShigella flexneri

    Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA caus...

    Synonyms: Recombinase A
  8. Target

    Monoamine oxidase

    go.drugbank.com/bio_entities/BE0004909
    TargetEnzymeHumans

    Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amin...

    Polypeptides: Amine oxidase [flavin-containing] ASynonyms: MAO-A, Monoamine oxidase type A
  9. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    Leucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis. … [L56091, L56092] Historically developed in 1945, leucovorin has long been a staple on the World Health Organization’s List of Essential Medicines.

    Categories: Compounds used in a research, industrial, or household setting, Vitamin B ComplexSynonyms: N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid, L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
  10. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. … It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.

    Mixtures: Nox-A-Sting, Soothe-A-stingCategories: Compounds used in a research, industrial, or household setting, NMDA Receptor Antagonists