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Alitretinoin
go.drugbank.com/drugs/DB00523ApprovedIt is used in the treatment of psoriasis; acne vulgaris; and several other skin diseases. It has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute). … An important regulator of gene expression during growth and development, and in neoplasms.
Letermovir
go.drugbank.com/drugs/DB12070ApprovedInvestigationalLetermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. … It is currently marketed under the brand name Prevymis.[L1021]
Betaine
go.drugbank.com/drugs/DB06756ApprovedInvestigationalNutraceuticalBetaine is a methyl group donor that functions in the normal metabolic cycle of methionine. … [L43105] Although it is present in many food products, the levels found there are insufficient to treat this condition.
Synonyms: 2-N,N,N-trimethylammonio acetate, N,N,N-TrimethylglycineMixtures: Face It Hd Perfect Bb Spf30 Pa 02, Face It Hd Perfect Bb Spf30 Pa 01Anastrozole
go.drugbank.com/drugs/DB01217ApprovedInvestigational[A186877,A186955] Anastrozole was first approved for use in the United States in 1995.[L8863] … Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to [letrozole], used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer
Ritonavir
go.drugbank.com/drugs/DB00503ApprovedInvestigationalAmerican Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) guidelines recommend ritonavir-boosted combination therapies as first-line therapy for … It is now more commonly used as a booster of other protease inhibitors and is available in both liquid formulations and as capsules.
Mixtures: VIRONTAR N COMPRIMIDOS RECUBIERTOS, VIRONTAR N COMPRIMIDOS RECUBIERTOSCategories: Antivirals used in combination for the treatment of HIV infectionsLactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approvedA normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. … Lactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.[L14120]
Mixtures: Dextrose in Lactated Ringers, D5-LRI (5% DEXTROSE IN LOCTATED RINGER'S INJ.)Peginterferon alfa-2a
go.drugbank.com/drugs/DB00008ApprovedInvestigationalHCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. … , and reduced all-cause mortality [A19626].
Categories: Compounds used in a research, industrial, or household setting, Interferon Type ISynonyms: PEG-IFN alfa-2AIngenol mebutate
go.drugbank.com/drugs/DB05013ApprovedWithdrawnPEP005 also has potent anti-leukemic effects, inducing apoptosis in myeloid leukemia cell lines and primary AML cells at nanomolar concentrations. … Ingenol mebutate was approved by the FDA in January 2012, and it is marketed under the name Picato®. Picato gel is indicated for the topical treatment of actinic keratosis.
Pertussis vaccine
go.drugbank.com/drugs/DB15274ApprovedInvestigationalPertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy).
Mixtures: Boostrix Injektionssuspension in einer Fertigspritze, dTaP Booster Injektionssuspension in einer Fertigspritze