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Chlortetracycline
go.drugbank.com/drugs/DB09093ApprovedVet approvedWithdrawnChlortetracycline is a tetracycline antibiotic, and historically the first member of this class to be identified. It was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of...
Mixtures: Aureocort 1 mg/g + 30 mg/g SalbeCategories: Antibiotics for Topical Use, Antibacterials for Systemic UseProparacaine
go.drugbank.com/drugs/DB00807ApprovedVet approvedIt is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
International brands: Ak-TaineLumacaftor
go.drugbank.com/drugs/DB09280ApprovedInvestigationalLumacaftor is a drug used in combination with [DB08820] as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. … Consequently, lumacaftor increases successful production of CFTR ion channels and the total number of receptors available for use at the cell membrane for fluid and ion transport.
Methylphenidate
go.drugbank.com/drugs/DB00422ApprovedInvestigational[L6037] CADDRA recommends the use of methylphenidate due to long term studies, of over twenty years in duration, which show methylphenidate is safe and effective. … The MLRTM release system allows for a sustained effect for 10-12 hours, allowing for once-daily dosing that covers the major times that ADHD impairment might occur (such as school, homework periods, during
Categories: Psychostimulants, Agents Used for ADHD and NootropicsSetmelanotide
go.drugbank.com/drugs/DB11700ApprovedInvestigationalSetmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. … [A224449] Other earlier treatments for these patients included gastric bypass surgery.[A224449] Patients taking setmelanotide experienced an average weight loss of 0.6 kg/week.
Chloroform
go.drugbank.com/drugs/DB11387ApprovedVet approvedWithdrawnChloroform is part of the FDA drug products withdrawn or removed from the market for reasons of safety or effectiveness.[L43942] … It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE and refrigerants, but the latter application is declining.
Categories: Compounds used in a research, industrial, or household settingBosutinib
go.drugbank.com/drugs/DB06616ApprovedInvestigational[A6901,A17961] Bosutinib was first approved by the FDA in 2012 for the treatment of adult chronic, accelerated, or blast-phase Ph+ CML with resistance or intolerance to prior therapy. … [L48436] On September 26, 2023, bosutinib was also approved by the FDA for the treatment of pediatric CML that is newly diagnosed or resistant/intolerant to prior therapy.
Lenacapavir
go.drugbank.com/drugs/DB15673ApprovedInvestigationalHIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens. Lenacapavir is a first-in-class ...
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseGallium Ga-68 gozetotide
go.drugbank.com/drugs/DB16019ApprovedInvestigational[L43542] In December of the same year, the drug was fully authorized by the EMA.[L44682] In Octer 2022, Ga-68 PSMA-11 was approved by Health Canada for diagnostic use in men with prostate cancer. … In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended Ga-68 gozetotide be granted marketing authorization for the diagnosis of prostate cancer.
Categories: Compounds used in a research, industrial, or household settingSodium stibogluconate
go.drugbank.com/drugs/DB05630ApprovedInvestigationalSodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). … Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials.