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Eprosartan
go.drugbank.com/drugs/DB00876ApprovedInvestigationalEprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Mixtures: TEVETEN PLUS 600 MG/12.5 MG FİLM KAPLI TABLET, 28 ADET, TEVETEN PLUS 600 MG/12.5 MG FİLM KAPLI TABLET, 56 ADETProducts: TEVETEN 600 MG FILM KAPLI TABLET, 28 ADETAnthralin
go.drugbank.com/drugs/DB11157ApprovedAnthralin (1,8‐dihydroxy‐9anthrone, dithranol) is an older anti-psoriatic agent that was first synthesized as a derivative of chrysarobin, obtained from the araroba tree in Brazil over 100 years ago. … It is important to consider that the drug is relatively innocuous, yet effective, and systemic side effects have not been observed with this anthralin, in contrast to a wide variety of systemic and topical
Vepdegestrant
go.drugbank.com/drugs/DB19006ApprovedInvestigational[A275507, A275509] It serves as an advanced option to address the clinical challenge of endocrine-resistant breast cancer subtypes. … [A275507, A275508, A275511] It was identified through a targeted medicinal chemistry optimization campaign to act as a next-generation endocrine therapy for breast cancer.
Cladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigationalCladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and T lymphocytes. … [A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell
Products: MAVENCLAD 10 MG TABLET, 1 ADET, MAVENCLAD 10 MG TABLET, 4 ADETMegestrol acetate
go.drugbank.com/drugs/DB00351ApprovedInvestigationalVet approvedA progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. … It has also been used in the palliative treatment of breast cancer.
Categories: Sex Hormones and Modulators of the Genital SystemProducts: BOREA 160 MG TABLET, 30 ADET, MEGACE 160 MG TABLET, 30 ADETOftasceine
go.drugbank.com/drugs/DB11184ApprovedOftasceine is also referred to as Fluorexon. It is used in ophthalmic solutions as a staining agent when fitting soft and hard lenses. It is a fluorescent dye or luminescent agent.
Chenodeoxycholic acid
go.drugbank.com/drugs/DB06777ApprovedInvestigationalIt can also reduce the amount of other bile acids that can be harmful to liver cells when levels are elevated. … Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body.
Products: CETEİX 250 MG SERT KAPSÜL, 100 ADET, KENDEO 250 MG SERT KAPSÜL, 100 ADETSorbitol
go.drugbank.com/drugs/DB01638ApprovedInvestigationalIt was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. … A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose.
Categories: Diet, Food, and Nutrition, Compounds used in a research, industrial, or household settingNalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalA narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. … Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigationalextensively investigated as an immunosuppressive and antitumour agent. … survival. mTOR is an important therapeutic target for various diseases, as it was shown to regulate longevity and maintain normal glucose homeostasis.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: RAPAMUNE 1 MG FILM DRAJE, 30 ADET, RAPAMUNE 0.5 MG TABLET, 30 ADET