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Displaying results 1431 - 1440 of 10000 in total
  1. Target

    G protein-coupled receptor family C group 5 member D

    go.drugbank.com/bio_entities/BE0010290
    TargetHumans

    G protein-coupled receptor involved in hard keratin expression and likely plays a role in the development of hair and nails

    Polypeptides: G protein-coupled receptor family C group 5 member DFunction: G protein-coupled receptor activity
  2. Drug

    Oxycodone

    go.drugbank.com/drugs/DB00497
    ApprovedIllicitInvestigational

    [Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460] … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics

    Mixtures: OSSICODONE E NALOXONE EG, OSSICODONE E NALOXONE EGCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  3. Drug

    Proline

    go.drugbank.com/drugs/DB00172
    ApprovedInvestigationalNutraceutical

    Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. … Proline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon-nitrogen double bond.

    Mixtures: Clinimix E, Clinimix E
  4. Drug

    Candesartan cilexetil

    go.drugbank.com/drugs/DB00796
    ApprovedInvestigational

    Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. … Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents

    Mixtures: CANDESARTAN E IDROCLOROTIAZIDE EG, CANDESARTAN E IDROCLOROTIAZIDE EGCategories: Agents Acting on the Renin-Angiotensin System, Angiotensin 2 Receptor Blocker
  5. Drug

    Pegsitacianine

    go.drugbank.com/drugs/DB19098
    Investigational

    Pegsitacianine is under investigation in clinical trial NCT05576974 (A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence … Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)).

  6. Drug

    Glycyrrhiza glabra

    go.drugbank.com/drugs/DB14312
    ApprovedInvestigationalWithdrawn

    Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Toe Corrector CompositeSynonyms: Ae-licorice, Glycyrrhizae Radix Et Rhizoma (Glycyrrhiza Glabra)
  7. Drug

    Epinastine

    go.drugbank.com/drugs/DB00751
    Approved

    to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory chemical mediators from the blood vessel to halt progression of the allergic … It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding

    Mixtures: FLURINOL(R) D COMPRIMIDOS DE LIBERACION MODIFICADACategories: Serotonin Receptor Antagonists, Serotonin 5-HT2 Receptor Antagonists
  8. Drug

    Ferric pyrophosphate

    go.drugbank.com/drugs/DB09147
    ApprovedInvestigational

    The ferric ion is strongly complexed by pyrophosphate.[A31979] It presents an increasing interest as this insoluble form can be milder in the gastrointestinal tract and present higher bioavailability. … Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma.

    Mixtures: Timosome Fe
  9. Drug

    Arsthinol

    go.drugbank.com/drugs/DB08928
    Experimental

    Considered well tolerated when compared to other related trivalent organoarsenicals, arsthinol has even undergone recent studies as a potential anticancer agent. … Friedheim in 1949 via the complexing of acetarsol with 2,3-dimercaptopropanol. It has since been demonstrated that the agent possesses activity against amoebas and yaws.

  10. Drug

    Iodine

    go.drugbank.com/drugs/DB05382
    ApprovedInvestigational

    Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]

    Mixtures: Ni-C-E-LE Plus, Vitafol Fe Plus