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Displaying results 1431 - 1440 of 10000 in total
  1. Drug

    Tirzepatide

    go.drugbank.com/drugs/DB15171
    ApprovedInvestigational

    [L48766] On September 15, 2022, tirzepatide was also approved by the European Commission.[L44386]. On November 02, 2023, tirzepatide was also approved by the Health Canada [L52800] … [A246260] Its protein sequence was based on the sequence of endogenous GIP, and its pharmacological action on GLP-1 receptors is comparable to endogenous GIP; however, the long half-life of tirzepatide

    Categories: Drugs Used in DiabetesProducts: Mounjaro 2.5 mg solution for injection in pre-filled pen, Mounjaro 5 mg solution for injection in pre-filled pen
  2. Drug

    Methylchloroisothiazolinone

    go.drugbank.com/drugs/DB14197
    Approved

    It is found within many commercially available cosmetics, lotions, and makeup removers. … Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties.

    Synonyms: 5-Chloro-N-methylisothiazolin-3-oneCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Protein C

    go.drugbank.com/drugs/DB11312
    ApprovedInvestigational

    Protein C is available in concentrated form as the product Ceprotin, which is indicated for use in pediatric and adult patients with severe congenital protein C deficiency for the prevention and treatment … It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to Activated Protein C (APC).

    Mixtures: Beriplex P/n 500, Beriplex P/n 1000
  4. Drug

    Poloxamer 188

    go.drugbank.com/drugs/DB11333
    Approved

    P188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217]. … The ability of P188 in attenuating membrane damage and cell injury has been demonstrated in a variety of _in vivo_ and _in vitro_ models [A27218].

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Rose bengal

    go.drugbank.com/drugs/DB11182
    ApprovedInvestigational

    A direct cytotoxic effect of Rose bengal on microorganisms and cancer cells has been observed, questioning its potential antitumor actions via intralesional injections. … Rose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Cytarabine

    go.drugbank.com/drugs/DB00987
    ApprovedInvestigational

    A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)

    Products: CYTARABINE CS INJ 1000MG IN 10ML
  7. Drug

    Flotufolastat F-18

    go.drugbank.com/drugs/DB17851
    ApprovedInvestigational

    therapy or suspected recurrence based on elevated serum prostate-specific antigen (PSA) level. … [A259846] In May 2023, the FDA approved the use of flotufolastat F-18 for PET of PSMA-positive lesions in men with prostate cancer with suspected metastasis who are candidates for initial definitive

  8. Drug

    Inositol

    go.drugbank.com/drugs/DB13178
    ApprovedInvestigationalWithdrawn

    It is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin because even though its presence is vital in the body, a deficiency in this molecule does not translate … These molecules have structural similarities to glucose and are involved in cellular signaling.

    Mixtures: Revitex Ampoules Et Comprimes, Doctor's Choice Brand for Men
  9. Drug

    Datopotamab deruxtecan

    go.drugbank.com/drugs/DB16410
    ApprovedInvestigational

    [L52130,L52220] In June 2025, it was granted an accelerated approval by the FDA for the treatment non-small cell lung cancers with EGFR mutations.[L53623] … Datopotamab deruxtecan is an antibody-drug conjugate comprising a Trop-2-directed monoclonal antibody (datopotamab) and a DNA topoisomerase-I inhibitor, DDx.

  10. Target

    F-box-like/WD repeat-containing protein TBL1X

    go.drugbank.com/bio_entities/BE0012106
    TargetHumans

    F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units (PubMed:14980219).

    Polypeptides: F-box-like/WD repeat-containing protein TBL1X