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Human varicella-zoster immune globulin
go.drugbank.com/drugs/DB11621ApprovedInvestigationalIt is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the disease severity in high-risk patients who … lack evidence of immunity to varicella and for whom varicella vaccine is contraindicated.
Zoliflodacin
go.drugbank.com/drugs/DB12817ApprovedInvestigationalGonorrhea, caused by Neisseria gonorrhoeae, presents a significant public health challenge due to increasing antimicrobial resistance. … [A275268] Zoliflodacin is a first-in-class spiropyrimidinetrione antibiotic designed to address this need by inhibiting bacterial type II topoisomerases (DNA gyrase and topoisomerase IV), thereby blocking
Mecamylamine
go.drugbank.com/drugs/DB00657ApprovedInvestigationalA nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. … Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Pectin
go.drugbank.com/drugs/DB11158ApprovedInvestigationalVet approvedThis status allows pectin to be used with no limitations.[L1960] … Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants.[A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4.
Mixtures: Kaolin Mixture W Pectin Nf, OPTAZOL-KOCamphor
go.drugbank.com/drugs/DB01744ApprovedInvestigationalWithdrawnIt appears in the list of drug products withdrawn or removed from the market for safety or effectiveness. … The FDA ruled that camphorated oil could not be marketed in the United States and that no product could contain a concentration higher than 11%.
Synonyms: Camphor D-formMixtures: Zam-Buk Ointment, Delsym No Mess Vapor Roll OnSutilain
go.drugbank.com/drugs/DB09379ApprovedWithdrawnIt is able to dissolve the intercellular matrix which helps with desquamation. … Sutilain contains proteolytic enzymes derived from _Bacillus subtilis_ and it is available as a cream-colored odorless powder.
Zotepine
go.drugbank.com/drugs/DB09225ApprovedWithdrawn[L1082] When the analysis of antipsychotics was retaken in 2016 by the FDA, zotepine did not reach the threshold effect to be further studied.[L1313]. … It was designed and synthesized by Fujisawa Pharmaceutical Co Ltd.[A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approved[A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders.
Mixtures: Throwers Pbc No. 1, FITODERM TCProducts: BETADERM T (BETAMETASONA0.05 % CREMA)Isavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalIt is proposed that the intravenous and oral dosing can be used interchangeably [L1482], without the need for a repeat loading dose when transitioning from an IV to an oral formulation [A32026]. … Following administration, isavuconazonium undergoes biotransformation to form the active moiety, isavuconazole, for the antifungal actions.
Torasemide
go.drugbank.com/drugs/DB00214ApprovedInvestigational[A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257]
Synonyms: N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide