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Displaying results 1441 - 1450 of 10000 in total
  1. Drug

    Pralatrexate

    go.drugbank.com/drugs/DB06813
    ApprovedInvestigational

    [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and is upregulated by oncogenes. … [A246703] As such, pralatrexate is thought to have a better therapeutic window compared to other antifolate analogs due to the novel target of RFC.

    Synonyms: 10-Propargyl-10-deazaaminopterin, N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acidProducts: DIFOLTA 20 MG/ML SOLUCION PARA INFUSION, SOLUTION FOR INFUSION 20MG/ML
  2. Drug

    Dolasetron

    go.drugbank.com/drugs/DB00757
    ApprovedInvestigational

    Dolasetron is a highly specific and selective serotonin 5-HT3 receptor antagonist.

    Products: Anzemet Injection 20 mg/ml
  3. Drug

    Maritime pine extract

    go.drugbank.com/drugs/DB15786
    Investigational

    Categories: Compounds used in a research, industrial, or household settingSynonyms: French maritime pine bark extract
  4. Drug

    Daunorubicin

    go.drugbank.com/drugs/DB00694
    ApprovedInvestigational

    A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione
  5. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. … It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.

    Mixtures: De La Cruz Tincture of Iodine, 10 Person ANSICategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Guanfacine

    go.drugbank.com/drugs/DB01018
    ApprovedInvestigational

    Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release

    Products: GUAGO 1 MG UZATILMIŞ SALIMLI TABLET, 7 ADET, GUAGO 2 MG UZATILMIŞ SALIMLI TABLET, 7 ADET
  7. Drug

    Chloramphenicol succinate

    go.drugbank.com/drugs/DB07565
    Approved

    [A192987] Chloramphenicol is a bacteriostatic antibiotic.[A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: GEMYSETIN SÜKSİNAT 1G I.M./ I.V. ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 100 FLAKON, SUMICLORAN ® 1 G INYECTABLE
  8. Drug

    Magnesium cation

    go.drugbank.com/drugs/DB01378
    ApprovedInvestigationalNutraceuticalWithdrawn

    Magnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. … When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend

    Mixtures: KALSİMAG-D3 1000 MG/300 MG/880 IU EFERVESAN GRANÜL, 30 ADET, KALSİMAG-D3 1000 MG/300 MG/880 IU EFERVESAN GRANÜL, 40 ADETSynonyms: Magnesium, ion(Mg2+)
  9. Drug

    Idursulfase

    go.drugbank.com/drugs/DB01271
    ApprovedInvestigational

    Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. … Idursulfase is a 525-amino acid glycoprotein with a molecular weight of approximately 76 kilodaltons.

    Synonyms: Alpha-L-iduronate sulfate sulfataseProducts: ELAPRASE 2 MG/ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, Elaprase (TM) Solution for Intravenous Infusion 2mg/ ml
  10. Drug

    Cefepime

    go.drugbank.com/drugs/DB01413
    ApprovedInvestigational

    Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994.

    Products: POZINEG® 1000 MG, POZINEG 1000