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Mefenamic acid
go.drugbank.com/drugs/DB00784ApprovedA non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: N-(2,3-xylyl)-2-aminobenzoic acid, N-2,3-xylylanthranilic acidTrastuzumab deruxtecan
go.drugbank.com/drugs/DB14962ApprovedInvestigationalTrastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. … [L10842] It is classified as an antibody-drug conjugate. The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of its class.
Categories: MATE 2 Substrates, P-glycoprotein substratesSynonyms: T-DXd, T- DXdPromazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnA phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. … It is currently not approved for use in the United States.
Categories: Dopamine D2 Receptor Antagonists, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine, N-(3-Dimethylaminopropyl)phenothiazineTrastuzumab emtansine
go.drugbank.com/drugs/DB05773ApprovedInvestigationalTrastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent … Trastuzumab emtansine is marketed under the brand name Kadcyla and is indicated for use in HER2-positive, metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: T-DM1Nonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnIt is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market. … N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 26-(Nonylphenoxy)-3,6,9,12,15,18,21,24-octaoxahexacosan-1-ol, Nonoxynol 9Diazoxide
go.drugbank.com/drugs/DB01119ApprovedInvestigational[A255647,L44612] In March 2025, an extended-release formulation of diazoxide choline was approved by the FDA for the treatment of hyperphagia in patients with Prader-Willi syndrome, becoming the first … In September 2015, the FDA issued a safety alert regarding post-marketing reports of pulmonary hypertension occurring in infants and neonates.
Categories: Arteriolar Smooth Muscle, Agents Acting On, combinations of sulfonamidesSynonyms: 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxideAmylocaine
go.drugbank.com/drugs/DB09088ApprovedWithdrawnElsewhere in English speaking countries it was referred to as Stovaine, given the meaning of the French word 'fourneau' as 'stove' in English [L1882]. … , and prilocaine in the 1940s and 1950s superseded and made the use of amylocaine obsolete.
Synonyms: 1-(Dimethylamino)-2-methyl-2-butanol benzoateProducts: Dentition Sirop DeAurothioglucose
go.drugbank.com/drugs/DB09121ApprovedWithdrawnContemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis [A32326]. … Many if not most gold compounds that were indicated for rheumatoid arthritis therapy have since been replaced with the use of various current disease modifying anti-rheumatic drugs (DMARDs) like methotrexate
International brands: Solganal BProducts: Solganal Inj 50mg/mlPralidoxime
go.drugbank.com/drugs/DB00733ApprovedInvestigationalVet approvedOrganophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. … Pralidoxime is an antidote to organophosphate pesticides and chemicals.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-PAMPentamidine
go.drugbank.com/drugs/DB00738ApprovedInvestigationalAntiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. … It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: p,p'-(pentamethylenedioxy)dibenzamidine, 1,5-bis(4-amidinophenoxy)pentane